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Completed

NCT Number: NCT04754529

Yoga Intervention for the Improvement of Cancer-Related Stress in Cancer Survivors

This clinical trial develops and test a yoga intervention in improving cancer-related stress in cancer survivors. The online hatha yoga intervention of breathing and movement incorporates both restorative poses, breathing techniques, guided meditation and may reduce stress levels and improve overall quality of health in cancer survivors.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Roswell Park Cancer Institute

Buffalo, New York, 14263, United States

About this study

PRIMARY OBJECTIVE:

I. To develop and test the feasibility of a standardized 12-week online hatha yoga intervention (n=30) of breathing and movement incorporating both restorative poses, breathing techniques, guided meditation.

SECONDARY OBJECTIVES:

I. To evaluate the yoga intervention in relation to self-reported levels of stress and quality of life in cancer survivors (n=30).

II. Feasibility of collecting blood and saliva at baseline and post-intervention for stress biomarkers, including cortisol and norepinephrine.

EXPLORATORY OBJECTIVE:

I. To determine how behavior change, quality of life (QoL), and biomarkers of adrenergic stress, inflammation, and immunosuppression are affected by a 12-week online yoga program completed by cancer survivors.

OUTLINE:

Patients receive online yoga intervention once a week (QW) for 12 weeks.

After completion of study, patients are followed up at 3 months.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age >= 18 years of age
  • Have been diagnosed with a cancer and have finished treatment
  • Have been cleared for physical activity by a physician or nurse practitioner (physician or nurse practitioner name and date clearance received)
  • Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure

Exclusion criteria

  • Unwilling or unable to complete the assessment in English
  • Are pregnant or nursing
  • Are unwilling or unable to follow protocol requirements
  • Have skeletal instabilities and/or cardio-pulmonary comorbidities
  • Have any condition which in the investigator's opinion deems the subject an unsuitable candidate to participate in this study

Treatment and study plan

Quality-of-Life Assessment

Other

Ancillary studies

Other names: Quality of Life Assessment

Survey Administration

Other

Ancillary studies

yoga

Other

Receive yoga intervention

Other names: Yoga Therapy

Primary outcomes

  1. Proportion of subjects who participate or show high adherence to the intervention

    Time frame: Up to 12 weeks

    Will be presented as observed proportion and 95% Clopper-Pearson confidence intervals (CIs).

Secondary outcomes

  1. Efficacy of the intervention in stress-reduction

    Time frame: Up to 3 months post-intervention

    Serum cortisol and norepinephrine levels will be measured by blood collection

  2. Efficacy of the intervention in stress-reduction

    Time frame: Up to 3 months post intervention

    Self report stress

  3. Efficacy of the intervention in stress reduction

    Time frame: Up to 3 months post intervention

    salivary cortisol will be measured by saliva collection

Other outcomes

  1. Change in Quality of life

    Time frame: Up to 3 months post-intervention

    Quality of life collected by the EORTC Quality of Life Questionnaire

  2. Change in Cognitive function

    Time frame: Up to 12 weeks

    Cognitive function will be assessed by standard questionnaires

Sponsors and collaborators

Lead sponsor

Roswell Park Cancer Institute

Other

Registry information

Official study title

Influence of Yoga on Cancer-Related Stress in Cancer Survivors

Important dates

Study start
2021
Primary completion
2024
Study completion
2024
First posted
Feb 15, 2021
Registry last updated
Jun 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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