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NCT Number: NCT07141953

Yoga in Women With Surgical Menopause After Gynecological Cancer

This randomized controlled trial investigates the effects of yoga on quality of life, sleep quality, and spiritual well-being in women who have entered surgical menopause after gynecological cancer surgery. Yoga is expected to be a supportive intervention for symptom management and to improve overall well-being in this patient population.

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Key information

Age range

18 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Dokuz Eylul University

Izmir, Balçova, 35330, Turkey (Türkiye)

Location contact

Dilek Bilgiç, Prof.

SUB_INVESTIGATOR

Nuri Yıldırım, Assoc.

SUB_INVESTIGATOR

Selcan Zeynep Ergöz Aksoy, RN. MSc.

CONTACT

[email protected]

+905393692241

Selcan Zeynep Ergöz Aksoy, RN. MSc.

PRINCIPAL_INVESTIGATOR

About this study

Surgical menopause after gynecological cancer surgery is associated with sudden and severe symptoms that may reduce quality of life, disturb sleep, and affect overall well-being. Supportive non-pharmacological approaches such as yoga may help manage these challenges.

This randomized controlled trial will investigate the effects of an 8-week yoga program on quality of life, sleep quality, and spiritual well-being in women who have entered surgical menopause. Forty-six participants will be randomly assigned to either a yoga intervention group or a control group. The intervention group will attend two yoga sessions per week (one online, one face-to-face) in small groups or individually with a certified instructor, while the control group will receive usual care and be offered yoga after the study.

Assessments will be conducted at baseline, post-intervention (8 weeks), and 3-month follow-up using standardized questionnaires. It is expected that yoga will support symptom management and improve overall well-being in this patient population.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age between 18-65 years Diagnosis of primary gynecological cancer (ovarian, endometrial, cervical, vaginal, or vulvar) (Stage I-III) Ability to read, understand, and speak Turkish Completion of all adjuvant treatments (surgery, chemotherapy, and/or radiotherapy) at least 6 months prior Access to the internet Having a computer/tablet/phone with a camera Willingness and ability to attend at least 80% of the yoga sessions Voluntary participation in the study

Exclusion criteria

Any condition that prevents communication Cognitive, sensory, or physical impairment that prevents yoga practice Diagnosis of metastatic gynecological cancer Regular yoga practice within the last 6 months (at least once a week for 8 consecutive weeks)

Treatment and study plan

Yoga

Behavioral

Participants in the intervention group will take part in an 8-week yoga program designed for women who have entered surgical menopause after gynecological cancer surgery. The program will consist of two 60-minute sessions per week, one delivered online and one delivered face-to-face, conducted in small groups (5-6 participants) or individually, depending on participant availability. The sessions will include physical postures, breathing exercises, and relaxation/meditation techniques. The program will be delivered by a certified yoga instructor.

Primary outcomes

  1. Change in Quality of Life with yoga

    Time frame: Baseline, 2 months (end of intervention), and 5 months (3-month follow-up)

    Change in WHOQOL-BREF total score. Scores range 0-100; higher scores indicate better quality of life.

Secondary outcomes

  1. Change in Sleep Quality

    Time frame: Baseline, 2 months (end of intervention), and 5 months (3-month follow-up)

    Change in Pittsburgh Sleep Quality Index (PSQI). Higher scores indicate worse sleep quality.

  2. Change in Spiritual Well-Being

    Time frame: Baseline, 2 months (end of intervention), and 5 months (3-month follow-up)

    Change in FACIT-Sp-12 total score. Higher scores indicate greater spiritual well-being.

  3. Change in Menopausal Symptoms

    Time frame: Baseline, 2 months (end of intervention), and 5 months (3-month follow-up)

    Change in Menopause Rating Scale total score. Higher scores indicate greater symptom burden.

Study contacts

Contact information is provided by the study sponsor or research team.

Selcan Zeynep Ergöz Aksoy, RN. MSc.

CONTACT

[email protected]

+905393692241

Sponsors and collaborators

Lead sponsor

Dokuz Eylul University

Other

Registry information

Official study title

The Effect of Yoga on Quality of Life, Sleep Quality, and Spiritual Well-Being in Women Who Undergo Surgical Menopause Following Gynecological Cancer Surgery: A Randomized Controlled Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Aug 26, 2025
Registry last updated
Aug 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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