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Enrolling by Invitation

NCT Number: NCT07268547

Wrist Reduction Intervention: Supracondylar Technique for Radial Nerve Block vs. Hematoma Block (WRIST Block Study)

The purpose of this study is to compare different types of local anesthesia-a supracondylar radial nerve block, a hematoma block, or a combination of the two-for reducing pain in people with a broken wrist (distal radius fracture). This is being done to find out which method provides better pain relief after the injury and during treatment in the emergency room.

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Key information

Conditions

Wrist Fracture Arm Injuries Fractures, Bone Wounds and Injuries Wrist Fractures Wrist Injuries

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Sarasota Memorial Health Care System

Sarasota, Florida, 34239, United States

About this study

This study is testing different ways to provide pain relief before reducing a broken wrist. Participants will receive one of three techniques: (1) a nerve block where a doctor injects lidocaine near the radial nerve under ultrasound guidance; (2) a hematoma block where a doctor injects lidocaine into the area where the bone broke; or (3) both the nerve block and the hematoma block. Patients will be asked how much pain they feel before the numbing, after the numbing, and after the wrist is reduced.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years of age or older
  • Patients admitted to the ECC with a distal radius fracture requiring closed reduction
  • Patient must be willing and able to provide informed consent to the study

Exclusion criteria

  • Under 18 years of age
  • Pregnant
  • Prisoner
  • Allergy to lidocaine
  • Patients unable to provide informed consent and/or perform study-related activities
  • Patients undergoing procedural sedation
  • Patients may be excluded at the discretion of the investigator based on their clinical judgment, if the participant no longer meets criteria, and/or if the health or safety of the patient may be impacted by taking part in the study.

Treatment and study plan

Supracondylar radial nerve block

Procedure

Supracondylar radial nerve blocks given at the radial nerve not as the same location of the fracture site, prior to fracture reduction.

Hematoma Block

Procedure

Injection of analgesia into the hematoma that forms surrounding the wrist fracture.

Combination of blocks

Procedure

Supracondylar radial nerve block given first, followed by hematoma block, before fracture reduction.

Primary outcomes

  1. Pain levels comparison

    Time frame: Pain will be measured at (1) baseline, (2) after administering the assigned pain block(s), and after the (3) fracture reduction.

    Comparing pain levels among patients who are undergoing a wrist fracture reduction. Measured on a scale of 0-10, 0= no pain to 10= worst pain.

    Pain will be measured at (1) baseline, (2) after administering the assigned pain block (s), and after the (3) fracture reduction.

Secondary outcomes

  1. Amount of opioid medication needed to control pain.

    Time frame: Opioid medication prescribing will be assessed at baseline, time of admission to the emergency room, until the patient is discharged and they are no longer active in the study.

    The amount of opioid prescribed, if any, will be collected and recorded for comparison during patient's time in emergency room.

  2. Number of patients requiring conscious sedation.

    Time frame: Patients will be monitored for need of conscious sedation from baseline, time of enrollment in the study, until discharge from the emergency room, when they are no longer active in the study.

    The need for conscious sedation among patients undergoing wrist fracture reduction in emergency care center will be recorded and monitored for comparison between groups.

  3. Adverse Events Monitoring

    Time frame: From baseline, time the patient is admitted and enrolled into the study, until the patient is discharged and no longer active in the study.

    Adverse events associated with any of the blocks that are administered to patients undergoing a wrist fracture reduction in the emergency care center will be identified, monitored, and recorded for reporting.

Sponsors and collaborators

Lead sponsor

Sarasota Memorial Health Care System

Other

Registry information

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Dec 5, 2025
Registry last updated
Dec 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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