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Completed

NCT Number: NCT01974583

Wound-healing Improvement by Resurfacing Split-Thickness Skin Donor Sites With Thin Split-thickness Grafting

Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites.

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Key information

Conditions

Skin Graft Disorder Disorder of Skin Donor Site Wound Healing Disturbance of

Age range

5 year–56 year

Sex eligibility

All sexes

Study type

Observational

About this study

Background：Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites.

Methods: 192 consecutive patients undergoing split-thickness skin grafting were included in the study and the participants were randomly divided into three groups: Group A was regrafted with thin STSG, while, Group B and Group C were covered with the occlusive hydrocellular dressing and paraffin gauze, respectively. The three groups were compared regarding to the time of epithelialization, pain sensed by the patients and the scar formation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients who continuously received an STSG from January 2002 to December 2010 in Department of Burn and Plastic Surgery, Tangdu Hospital, Fourth Military Medical University

Exclusion criteria

  • The patients who were significant psychiatric, hypersensitive to silver, and not be followed up were excluded

Treatment and study plan

regrafted with thin split-thickness skin graft

Procedure

Group A (the treatment group) were regrafted with thin split-thickness skin graft

covered with the occlusive hydrocellular dressing

Procedure

group B covered with the occlusive hydrocellular dressing (Allevyn Adhesive, Smith & Nephew)

covered with paraffin gauze

Procedure

Group C covered with paraffin gauze

Primary outcomes

  1. The time of epithelialization

    Time frame: up to 4 weeks

    The time of epithelialization was observed every 3 days

Secondary outcomes

  1. Pain sensed by the patients

    Time frame: up to 6 months

    Pain sensed by the patients was assessed by Wong-Baker FACES Pain Rating Scale on day 2 and 5 after surgery

Other outcomes

  1. Scar formation of skin donor site

    Time frame: 1 year

    Scar formation of skin donor sites was evaluated by Vancouver scar scale in terms of colour, vascular distribution, thickness and scratchability 6-12 months after surgery

Sponsors and collaborators

Lead sponsor

Tang-Du Hospital

Other

Registry information

Important dates

Study start
2002
Primary completion
2010
Study completion
2013
First posted
Nov 1, 2013
Registry last updated
Nov 1, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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