Wound Healing Abnormalities in Major Abdominal Surgery

This clinical observational study investigates the incidence of wound healing abnormalities in patients undergoing major abdominal surgery. Second aim of the study is, if wound healing deficits may be accompanied by abnormalities in blood coagulation parameters.

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Key information

Conditions

Impaired Wound Healing Blood Coagulation Disorders Blood Coagulation Disorders, Inherited Cardiovascular Diseases Coagulation Protein Disorders Congenital, Hereditary, and Neonatal Diseases and Abnormalities Embolism and Thrombosis Factor XIII Deficiency Genetic Diseases, Inborn Hematologic Diseases Hemic and Lymphatic Diseases Hemorrhagic Disorders Thrombosis Vascular Diseases

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Klinikum St. Georg gGmbH

Leipzig, Saxony, 04105, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age >= 18 years
Male or female
Informed consent
Major abdominal surgery

Exclusion criteria

Pre-existing coagulation abnormalities
Pre-existing severe renal or liver failure
Chemo- or radiochemotherapy

Treatment and study plan

Primary outcomes

Incidence of wound healing abnormalities

Time frame: from baseline to postoperative day 28

Occurence of wound healing abnormalities within the first 28 days after surgery

Secondary outcomes

Abnormalities in coagulation parameters

Time frame: postoperative day 28

occurence of low platelets (<60.000) or factor XIII < 50% between the first and seventh postoperative day

Sponsors and collaborators

Lead sponsor

Klinikum St. Georg gGmbH

Other

Registry information

Official study title

Incidence of Wound-healing-abnormalities in Major Abdominal Surgery - Association With Factors of Coagulation

Acronym: INWOUND

Important dates

Study start: 2008
Primary completion: 2017
Study completion: 2017
First posted: Aug 15, 2008
Registry last updated: Apr 24, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed