Skip to main content
OpenTrials
Completed

NCT Number: NCT04316533

Work Stress and Impact of Pruritus on Quality of Life

Work stress and pruritus: imbalance of effort balance reward in patients with psoriasis.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Psoriasis Behavior Behavioral Symptoms Occupational Diseases Occupational Stress Pathological Conditions, Signs and Symptoms Pruritus Signs and Symptoms Skin Diseases Skin Diseases, Papulosquamous Skin Manifestations Skin and Connective Tissue Diseases Stress, Psychological

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Chru Brest

Brest, Finistère, 29609, France

About this study

Background. Stress increases the likelihood of psoriasis flare-up episodes and itching. Few studies have focused on work-related stress on such skin symptoms.

Objective. To study the association between work-related stress, pruritus and quality of life among workers suffering from psoriasis.

Methods. Investigators will conduct a monocentric non-interventional prospective study. Patients suffering from psoriasis will be recruited in both the Dermatology inpatient ward and outpatient clinic of Brest University Hospital . Included patients will be workers. Work-related stress will be assessed using the Effort-Reward Imbalance (ERI) model. The impact of pruritus on quality of life will be assessed with the Itchy Quality of Life (ItchyQoL) self-administered questionnaire. The collected data will include age, sex, body mass index, ordered medication to treat psoriasis, weekly working hours. The association between ERI and ItchyQoL scores will be studied using a univariate logistic regression.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Major patients
  • Active busy patients with psoriasis presenting for a dermatology consultation or hospitalization at the Brest CHRU
  • Participation agreement

Exclusion criteria

  • Presence of another potentially pruritic pathology
  • No command of the French language
  • Patient under legal protection (guardianship, curatorship, etc.)
  • Refusal to participate

Treatment and study plan

Primary outcomes

  1. Pruritus' impact on quality of life

    Time frame: time required to complete the self questionnaire estimated at approximately 5 min immediately after consultation with the dermatologist

    The Itchy Quality of Life questionnaire (ItchyQoL) assess the quality of life linked to pruritus. It is a 22-item questionnaire wich assess the frequency of pruritus'symptoms in the past seven days. The score is between 22 and 110. The higher the score, the greater the impact of pruritus.

Secondary outcomes

  1. Occupational stress

    Time frame: time required to complete the self questionnaire estimated at approximately 5 min immediately after consultation with the dermatologist

    The effort-reward imbalance questionnaire in 23-item for occupational stress. Six items make it possible to calculate the extrinsic efforts felt (score e) and eleven items assess the rewards perceived by the employee (score r). The ERI score is then calculated as follows: Ratio = (11 x e) / (6 x (66 - r)) (e: effort scale score, r: rewards scale score). A ratio greater than one indicates an imbalance in favor of efforts. The last six items make it possible to calculate the score for intrinsic efforts (over commitement). They relate to the inability to get away from work, impatience and disproportionate irritability.

Sponsors and collaborators

Lead sponsor

University Hospital, Brest

Other

Registry information

Official study title

Study of the Association Between Work Stress and the Impact of Pruritus on Quality of Life

Acronym: PRUERI

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Mar 20, 2020
Registry last updated
Jul 7, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.