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NCT Number: NCT06599788

Work Design Interventions for Heat Resilience

The goal of this project is to compare different ways to schedule a workday to see if older workers should follow a specific work protocol to reduce strain on the heart and muscles.

Participants will come to the lab a total of six times. During four of the visits participants will complete a box carrying task, simulating unloading a delivery truck. This will take place in a hot and humid room to simulate being outdoors during the summer.

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Key information

Conditions

Hyperthermia Body Temperature Changes Fatigue Fatigue; Heat Heat Stress Disorders Pathological Conditions, Signs and Symptoms Signs and Symptoms Work-Related Condition Wounds and Injuries

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy individuals
  • 18-29 years old and 40-65 years old
  • Completes at least 120 minutes of moderate to vigorous physical activity each week for at least the past 4 weeks
  • Resistance trained or have recently held a job involving box carrying or a similar task

Exclusion criteria

  • History of cardiovascular, metabolic, respiratory, neural, or renal disease
  • Hypertensive (systolic blood pressure > 139 mmHg or diastolic blood pressure > 89 mmHg) or tachycardic (resting heart rate > 100 bpm) during the screening visit
  • Current nicotine use or previous use within the past 6 months
  • Current of previous musculoskeletal injury limiting physical activity
  • A positive pregnancy test at any point during the study
  • Currently breastfeeding
  • Study physician discretion based on any other medical condition or medication

Treatment and study plan

Standard work pace

Behavioral

Participants will work at a standard pace of one box per minute during the box carrying protocol

Reduced-pace work

Behavioral

Participants will work at a slower pace than the standard work pace of the box carrying protocol

Increased-pace work

Behavioral

Participants will work at a faster pace than the standard work pace of the box carrying protocol

Additional rest breaks

Behavioral

Participants will work at the standard work pace during the box carrying protocol and have superimposed 5 minutes of rest every 30 minutes.

Primary outcomes

  1. Cardiac Troponin

    Time frame: 2 hours following work protocol, approximately 6 hours into the trial

    Serum cardiac troponin concentration

  2. Maximum Core Temperature

    Time frame: End of work protocol, approximately 4 hours into the trial

    Highest core temperature attained during the work protocol

Study contacts

Contact information is provided by the study sponsor or research team.

Riana Pryor

CONTACT

[email protected]

716-829-5456

Sponsors and collaborators

Lead sponsor

State University of New York at Buffalo

Other

Registry information

Important dates

Study start
2027
Primary completion
2029
Study completion
2029
First posted
Sep 19, 2024
Registry last updated
Jun 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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