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Completed

NCT Number: NCT01382576

Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity

In the present study, serum chitotriosidase activity and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS).

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Key information

Conditions

Polycystic Ovary Syndrome Adnexal Diseases Cysts Endocrine System Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Gonadal Disorders Neoplasms Ovarian Cysts Ovarian Diseases Urogenital Diseases

Age range

18 year–35 year

Sex eligibility

Female

Study type

Observational

Primary location

Gulhane School of Medicine Etlik

Ankara, 06180, Turkey (Türkiye)

About this study

ChT activity is increased in patients with PCOS in concordance with insulin resistance. These findings may reflect the pronounced risk for metabolic syndrome and atherosclerotic diseases in this particular patient group.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Absence of significant abnormalities on physical examination except hirsutism
  • no lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy
  • normal thyroid function and prolactin level
  • absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic disease

Exclusion criteria

  • Pregnant
  • ovarian tumors
  • congenital adrenal hyperplasia or BMI greater than 30 kg/m2

Sponsors and collaborators

Lead sponsor

Gulhane School of Medicine

Other

Registry information

Official study title

Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity: A Pathophysiological Link Between Inflammation and Impaired Insulin Sensitivity?

Important dates

Study start
2010
Primary completion
2010
Study completion
2010
First posted
Jun 27, 2011
Registry last updated
Mar 12, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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