Wholebody MRI In Lung Cancer StagiNg

Magnetic Resonnace Imaging (MRI) and Positron Emission Tomography (PET) can be both used in detection of nodes in patients with cell lung cancer (NSCLC).

However, the cardiorespiratory synchronization in the MRI, allowing acquisition of synchronous images with breathing and heart movements should increase the sensitivity of detection of pathologic mediastinal lymph nodes.

Given its high sensitivity, whole-body MRI with diffusion could possibly be at least as informative as PET, while being less expensive, not radiant.

The purpose of this study is to evaluate the performance of whole-body MRI with diffusion with cardiorespiratory synchronization, on the detection of mediastinal nodes (which are known to be less well detected by MRI) compared to PET.

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Key information

Conditions

Lung Cancer Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU Limoges

Limoges, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

At least 18 years,
Neoplasia bronchopulmonary (SCLC and NSCLC) newly diagnosed,
Patient potentially eligible for curative treatment, but no no treatment started,
Patients for whom a PET scan and MRI are planned

Non Inclusion Criteria:

claustrophobia,
Implantable Medical Device
not compatible pacemaker type or heart valve, metal splinters eye)
Pregnant or lactating women,

Treatment and study plan

MRI

Device

Whole body MRI with cardiac and pulmonary synchronization

PET

Device

Primary outcomes

Th consistency of the locations of mediastinal lesions

Time frame: Day 1

Node localization according to MRI and PET scan measurements on the same day

Sponsors and collaborators

Lead sponsor

University Hospital, Limoges

Other

Registry information

Official study title

Initial Staging of Bronchopulmonary Neoplasia: Whole-body MRI Versus Pet Scanner

Acronym: WISLON

Important dates

Study start: 2016
Primary completion: 2018
Study completion: 2019
First posted: Mar 23, 2016
Registry last updated: Jul 5, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed