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NCT Number: NCT07453641

White Noise and Crying Duration After Invasive Procedures in Infants

The aim of this study is to evaluate the effect of white noise applied during invasive procedures (blood sampling or intravenous access) on pain and physical parameters in infants aged 1-3 months.

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Key information

Conditions

White Noise Behavior Communication Crying Neurologic Manifestations Nonverbal Communication Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

1 month–3 month

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Basaksehir Cam ve Sakura City Hospital

Istanbul, Turkey (Türkiye)

Location status: Recruiting

About this study

White noise is a monotonous sound that mimics the intrauterine environment, protecting the baby from environmental noise and having a calming effect. The findings may demonstrate the effectiveness of white noise among non-pharmacological approaches to pain management in infants and may offer healthcare professionals an applicable intervention method. If the pain and stress-reducing effects of white noise are proven, its use in routine care could be expanded. There are no known side effects associated with white noise application. There is no risk beyond that of a normal blood draw during the procedure.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Infants aged 1-3 months
  • Born at term (≥37 weeks gestational age)
  • Admitted to the general pediatric ward
  • Scheduled for routine invasive procedures such as venipuncture or intravenous line placement

Exclusion criteria

  • Infants with congenital anomalies
  • Infants with hearing impairments
  • Infants with a history of analgesic or pain-relieving medication use prior to the invasive procedure
  • Infants requiring intensive care unit (ICU) monitoring

Treatment and study plan

White Noise Audio

Behavioral

Infants undergo routine invasive procedures while continuous white noise audio is played through speakers. Crying duration is measured immediately after each procedure to evaluate the effect of white noise on procedural distress.

Primary outcomes

  1. Crying Duration

    Time frame: Immediately after each invasive procedure (0-5 minutes)

Study contacts

Contact information is provided by the study sponsor or research team.

Esin YILDIZ ALDEMİR, MD, PhD

CONTACT

[email protected]

+905324859556

Sponsors and collaborators

Lead sponsor

Başakşehir Çam & Sakura City Hospital

Other Gov

Registry information

Official study title

The Effect of White Noise on Crying Duration After Invasive Procedures in Infants Aged 1-3 Months

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 6, 2026
Registry last updated
Mar 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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