Wedge Resection for Ground-glass Opacity-featured Lung Cancer (ECTOP-1020)

Inclusion criteria

• Patients who sign the informed consent form and are willing to complete the study according to the plan;
• Aged from 18 to 80 years old;
• ECOG equals 0 or 1;
• Not receiving lung cancer surgery before;
• Intraoperative or postoperative pathologic diagnosis of lung adenocarcinoma;
• Single lung nodules with ground-glass dominant or pure ground-glass on CT, or multiple lung nodules with the major lesion being the aforementioned nodules;
• The nodule has a consolidation-to-tumor ratio (CTR) between 0.25 and 0.5 (including 0.25 and 0.5), and the nodule size is less than or equal to 2 cm;
• peripheral type of nodes, namely, nodes in the outer 1/3 of the lung field.
• cT1N0M0 tumors;
• Complete tumor resection by wedge resection as assessed by the surgeon;
• Not receiving chemotherapy or radiotherapy before.

Exclusion criteria

• Postoperative pathologic diagnosis of adenocarcinoma in situ or minimally invasive adenocarcinoma.
• CTR is not between 0.25-0.5 or nodule size greater than 2 cm;
• Cannot be completely resected by wedge resection;
• Invasive lung adenocarcinoma or lung malignancy other than lung adenocarcinoma diagnosed cytologically or pathologically;
• Receiving lung cancer surgery before;
• Receiving radiotherapy or chemotherapy.