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NCT Number: NCT07309367

Web-based Advance Care Planning Intervention for Patients With Kidney Failure on Dialysis: Pilot Testing of 'My Voice'

'My Voice' is a website intervention developed to enable advance care planning (ACP) conversations for patients with kidney disease on dialysis, educate patients on their illness, help identify their goals and preferences for EOL care, and coaches them on how to speak with their HCPs and loved ones. This study aims to evaluate if 'My Voice' intervention improves quality of ACP conversations between patients and providers, and patients and family carers; improves patient's knowledge about kidney failure, engagement in ACP and preparedness for future end of life care compared to usual practices for ACP in dialysis centres.

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Key information

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Duke NUS Medical School

Singapore

Location status: Recruiting

Location contact

Chandrika Ramakrishnan, MBBS; MPH

CONTACT

[email protected]

+6566011253

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

For patients

  • Singapore citizens or permanent residents; aged 21 years (age of majority) or older
  • CKD stage 5; receiving dialysis
  • Identified as eligible for SIC by NKF HCPs based on one or more of the following:
  • clinical deterioration with a terminal condition or
  • intolerability to dialysis or
  • having two or more unplanned hospitalizations for renal complications in the past 6 months (from medical records); or
  • known to palliative care or under conservative care as indicated in the discharge summary or
  • poor functional status indicated by the Fragility Assessment for Elders (FIFE) score >4
  • Normal cognitive function as indicated by Mini Mental Scale Examination (MMSE) score of 24 or more (based on medical record)
  • Able to speak and read English, Mandarin or Malay
  • Agreeable to be audio-recorded

Inclusion criteria

For caregivers

  • Aged 21 years old and above
  • Family caregivers of the patients recruited i.e. Caregiver primarily involved in providing care, ensuring provision of care, and/or in making decisions regarding patient's care, with no expectation of financial compensation
  • Able to speak and read English, Mandarin or Malay
  • Have a phone and/or an electronic device with internet access.
  • Agreeable to be audio-recorded

Exclusion criteria

For Patients

  • Patients with cognitive impairment or serious mental illness will be excluded
  • Patients who had prior serious illness conversations (SIC) will be excluded
  • Are not easily contactable via mobile phone or landline

Exclusion criteria

For Caregivers

  • Those who are foreign domestic workers/maids
  • Are not easily contactable via mobile phone or landline

Treatment and study plan

My Voice website intervention with patient and caregiver modules

Other

'My Voice' is an interactive web-based ACP intervention tailored for patients with kidney failure on dialysis, and their caregivers, and includes patient and caregiver modules. Patient module has 6 steps consisting of a series of videos, value-clarification exercise (VCE) identifying goals and values for care, and knowledge quiz, and a summary My Voice document that is generated shared with patients, designated surrogates and HCPs. Automated reminders are sent to revisit My Voice. Caregiver module has 4 steps with videos and quiz, with access to their loved one's summary My Voice document containing goals of care and values.

Primary outcomes

  1. Quality of ACP conversations (serious illness conversations) between patients and physicians/health care providers

    Time frame: Post baseline and within 8 weeks

    Quality of ACP conversations will be measured using a scoring sheet developed for the study. One point will be given for every SICG topic discussed with score min to max of 0 to 13. Higher scores indicate higher quality.

Other outcomes

  1. Change in kidney disease and dialysis knowledge scores

    Time frame: Baseline to 8 weeks

    Collected using knowledge questions designed by the research team. Higher scores indicate higher knowledge

  2. Change in ACP engagement

    Time frame: Baseline to 8 weeks

    Using the 9-item Advance care planning engagement scale. 9 to 45 (Min to Max) value, with higher value indicating higher engagement

  3. Change in patient preparedness

    Time frame: Baseline to 8 weeks

    Assessed using Preparedness for end-of-life decision-making scale. 20 to 80 (min to max) scores, with higher scores indicating better preparedness

  4. Change in proportion of patients who had ACP conversations with family caregivers/spokesperson

    Time frame: Baseline and 8 weeks

    Based on self-reported number of ACP conversations collected in the survey

Study contacts

Contact information is provided by the study sponsor or research team.

Chandrika Ramakrishnan, MBBS; MPH

CONTACT

[email protected]

+6566011253

Sponsors and collaborators

Lead sponsor

Duke-NUS Graduate Medical School

Other

Collaborators

  • National Kidney Foundation, Singapore

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 30, 2025
Registry last updated
Dec 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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