Web-based Addiction Treatment: Cultural Adaptation With American Indians

The purpose of the current study is to evaluate the preliminary efficacy of the Therapeutic Education System-Native Version (TES-NAV) (an efficacious web-delivered psychosocial intervention for substance use disorders adapted with American Indians/Alaska Natives [AI/AN]) to determine whether a future large-scale effectiveness trial is warranted. Specifically, a randomized controlled trial among urban AI/AN (N=80) attending outpatient addiction treatment services will be conducted to (1) estimate preliminary effect size of 12 weeks of TES-NAV on substance use disorder outcomes; (2) explore relevant moderators of TES-NAV outcomes; and (3) assess cultural factors that may correspond to variation in outcome.

Completed

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Key information

Conditions

Substance Use Disorders Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Native American Rehabilitation Association of the Northwest, Inc.

Portland, Oregon, 97205, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

18 years of age or older
Identify as American Indian or Alaska Native
Recent alcohol or drug use
Within first 30 days of current outpatient treatment episode

Exclusion criteria

Planned treatment episode of less than 3 months
Insufficient ability to provide informed consent

Treatment and study plan

TES-NAV

Behavioral

Internet-delivered psychosocial treatment grounded in the community reinforcement approach plus contingency management adapted for AI/AN

TAU

Behavioral

Standard outpatient addiction treatment

Primary outcomes

Consecutive Weeks of Drug/Alcohol Abstinence

Time frame: 12 weeks (following randomization)

Each week was categorized as abstinent if the urine screen was negative and the self-report indicated no drug use and no heavy drinking days and not abstinent if either urine screen or self-report indicated drug use or heavy drinking. If the urine screen was missing, TLFB self-report data was used.

Sponsors and collaborators

Lead sponsor

New York State Psychiatric Institute

Other

Collaborators

National Institute on Drug Abuse (NIDA)

Registry information

Important dates

Study start: 2018
Primary completion: 2020
Study completion: 2020
First posted: Dec 6, 2017
Registry last updated: May 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed