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Recruiting

NCT Number: NCT07303920

Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day

The purpose of this study to assess the wear experience of people who have astigmatism when wearing a daily disposable contact lens for astigmatism over long days of wear.

Recruiting

Interested in participating?

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Key information

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Current soft toric contact lens wearer with long hours of wear
  • Willing to follow the contact lens wearing schedule required by the study
  • Vision 20/25 or better with current soft toric contact lenses
  • Self-report completion of a comprehensive eye examination in the past two years

Exclusion criteria

  • Have a history of corneal ocular surgery
  • Have current ocular inflammation or infection as assessed by the study investigator who will complete the study
  • Are past rigid contact lens wearers
  • Have a history of being diagnosed with dry eye or ocular allergies
  • Have known systemic health conditions that are thought to alter tear film physiology
  • Have a history of viral eye disease
  • Have a history of ocular surgery
  • Have a history of severe ocular trauma
  • Have a history of corneal dystrophies or degenerations
  • Have active ocular infection or inflammation
  • Are currently using isotretinoin-derivatives or ocular medications
  • Are pregnant or breast feeding

Treatment and study plan

Daily disposable contact lenses for astigmatism

Device

All participants will be fit with the study lenses

Other names: Dailies Total1 for Astigmatism

Primary outcomes

  1. Comfort

    Time frame: Measured over 16 hours of wear

    Proportion of participants with positive Visual Analog Scale (VAS, >50 on a 0-100 scale)

Study contacts

Contact information is provided by the study sponsor or research team.

Study Coordinators

CONTACT

[email protected]

614-292-8858

Sponsors and collaborators

Lead sponsor

Ohio State University

Other

Collaborators

  • Alcon Research

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Dec 26, 2025
Registry last updated
Mar 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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