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OpenTrials
Completed

NCT Number: NCT06530095

We Compared the Covid-19 Acute Respiratory Distress Syndrome (ARDS) Patients Who Applied Prone Positioning for16-24 Hours vs 24-48 Hours

The goal of this study is to understand if there is any improvement on oxygenation of patients diagnosed with Covid-19 ARDS patients when we extend the duration of prone positioning.

Second outcome of the study is to investigate mortality of patients when we extend the duration of prone positioning.

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Key information

Conditions

Morality Hypoxia Oxygenation Indices Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Respiratory

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Bakirkoy Dr Sadi konuk Research and Training hospital

Istanbul, 34450, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

COVİD 19 ARDS patients patients who have been intubated for 48 hours and more

Exclusion criteria

Pediatric patients Patients who extubated in less than 48 hours Patients with Lung and pleural malignancies

Treatment and study plan

Prone Positioning

Other

prone positioning

Primary outcomes

  1. Oxygen Saturation Index (OSI)

    Time frame: 48 hours

    OSI is calculated by dividing the product of mean airway pressure (MAP) and FiO2 with SpO2

  2. Oxygenation Index

    Time frame: 48 hours

    Oxygenation index is calculated as OI = MAP × Fio2 × 100 / Pao2, where MAP indicates mean airway pressure and Fio2 indicates fraction of inspired oxygen

Secondary outcomes

  1. ICU mortality

    Time frame: 28 days

    mortality rates during patients admission in the ICU

Sponsors and collaborators

Lead sponsor

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Other Gov

Registry information

Official study title

''Impact of Early vs. Delayed Prone Positioning on Oxygenation and Mortality in COVID-19 ARDS Patients: A Retrospective Analysis''

Important dates

Study start
2022
Primary completion
2023
Study completion
2024
First posted
Jul 31, 2024
Registry last updated
Jul 31, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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