The Carter Center
Addis Ababa, Ethiopia
NCT Number: NCT02373657
Trachoma is a blinding disease caused by ocular strains of Chlamydia trachomatis. The Carter Center and Proctor Foundation have been jointly conducting trachoma research in the Goncha Siso Enese woreda of Amhara for the past 8 years, through a series of clinical trials. We have found that repeated mass administration of oral azithromycin can greatly reduce the prevalence of trachoma, but mass antibiotics have been unable thus far to eliminate infection. The World Health Organization recommends not only antibiotics for control of trachoma, but an entire SAFE strategy (Surgery for in-turned eyelids, Antibiotics, Facial hygiene promotion, and Environmental improvements such as latrines and water points). Trachoma is more common in villages and households with poor access to water and latrines, so improving the public health infrastructure is thought to be important for limiting transmission of trachoma. However, there is very little evidence to support the efficacy of installing new water points for trachoma. There has been only one previous attempt to study the role of hand dug well installation for trachoma control, and this study, conducted in Niger, found that installing wells was not effective. We now propose a project to improve the public health infrastructure of Goncha Siso Enese woreda by helping with the construction of water points (e.g., hand-dug wells) and providing hygiene education, in order to determine whether improving access to water and hygiene information will be effective for control of trachoma and soil-transmitted helminths.
Looking for future studies?
Notify MeAll sexes
Interventional
Not applicable
Addis Ababa, Ethiopia
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 24 months
Time frame: 24 months
Time frame: 24 months
Time frame: 24 months
Time frame: 24 months
Time frame: 24 months
Time frame: 24 months
University of California, San Francisco
Other
Acronym: WUHA
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT02754583
Bacterial Infections, Bacterial Infections and Mycoses
Addis Ababa, Ethiopia
View Trial DetailsNCT04185402
Bacterial Infections, Bacterial Infections and Mycoses
Niamey, Niger
View Trial DetailsNCT03926728
Bacterial Infections, Bacterial Infections and Mycoses
London, United Kingdom
View Trial DetailsNCT05634759
Bacterial Infections, Bacterial Infections and Mycoses
Juba, South Sudan
View Trial Details