Skip to main content
OpenTrials
Completed

NCT Number: NCT03454594

Watch Laser Acupuncture With Nasal Radiation for Prevention of Coronary Artery Disease

This study will evaluate the effect of low level laser blood radiation applied to all participants for prevention of coronary artery disease in patients with high risk (hypertension,high blood viscosity, hypercholesterolemia as well as related immune issues)

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Cardiovascular Risk Factor Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Coronary Artery Disease Coronary Disease Dyslipidemias Heart Diseases Hypercholesterolemia Hyperlipidemias Hypertension Lipid Metabolism Disorders Metabolic Diseases Myocardial Ischemia Nutritional and Metabolic Diseases Vascular Diseases

Age range

55 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Cairo

Giza, Dokki, 11432, Egypt

About this study

The areas of low - intensity laser use have expanded in several conditions by different mechanisms and ways. Hypertension as one of coronary artery disease risk factors and early indicator of future cardiovascular events with high blood viscosity and elevated blood cholesterol levels with immune-pathological basis became necessary issue to be handled. Low Level Laser irradiation effects on blood is very essential way in revealing the mechanisms of the action of laser radiation on biological tissues by means of changes in metabolism, leading to molecular, cellular and systemic changes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • stage I hypertensive patients
  • patients from 30 to 34.9 kg/m2 body mass index
  • medically stable patients
  • all participants have sufficient cognition enough to understand the requirements of the study

Exclusion criteria

  • history of malignant disease
  • smoking
  • history of progressive fatal disease
  • history of drug or alcohol abuse
  • blood donation within at least 30 days
  • pregnant, trying to be pregnant or breast feeding
  • cognitive impairment that will make it difficult to partake in the study

Treatment and study plan

low level laser hemotherapy

Device

semiconductor laser therapeutic instrument irradiate the circulating blood in the vessels of left hand acupoint and the mucosal tissue in the nasal cavity

Other names: Watch laser

Primary outcomes

  1. changes of blood pressure

    Time frame: 8 weeks

    measuring blood pressure before and after each low level laser radiation

Secondary outcomes

  1. changes in blood viscosity

    Time frame: 8 weeks

    measuring changes in blood viscosity before and after low level laser radiation session

  2. change in IL-17 level

    Time frame: 45 days

    measuring changes in IL-17 level before and after low level laser radiation session

  3. change in functional capacity

    Time frame: 70 days

    measuring of 6 minute walking test before and after low level laser irradiation as an indicator of functional capacity improving

  4. change in CD 8 (cluster of differentiation 8) level

    Time frame: 45 days

    measuring changes in CD 8 (cluster of differentiation 8) level before and after low level laser radiation session

  5. change in TC (total cholesterol) level

    Time frame: 60 days

    measuring changes in TC (total cholesterol) level before and after low level laser radiation session

  6. change in LDL (low density lipoprotien) level

    Time frame: 60 days

    measuring changes in LDL (low density lipoprotien) level before and after low level laser radiation session

  7. change in TG (triglyceride) level

    Time frame: 60 days

    measuring changes in TG (triglyceride) level before and after low level laser radiation session

  8. change in HDL (high density lipoprotien) level

    Time frame: 60 days

    measuring changes in HDL (high density lipoprotien) level before and after low level laser radiation session

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Laser Hemotherapy Trial for Coronary Artery Disease Prevention in High Risk Patients

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Mar 6, 2018
Registry last updated
Feb 7, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.