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OpenTrials
Completed

NCT Number: NCT03025100

VTE Prophylaxis Guidelines in Hospitalized Elders

Guideline directed use of pharmacologic Venous thromboembolism (VTE) prophylaxis emphasizes mobility evaluation. Mobility is a key component of risk stratification. Poor mobility evaluation by providers may be a significant barrier to appropriate use of VTE prophylaxis. The investigators aim is to propose to determine whether level of mobility during hospitalization is being used to influence use and duration of VTE prophylaxis among medically ill hospitalized elders. To achieve this aim, the investigator will collect prospective observational data to objectively measure inpatient mobility using patient mounted accelerometers during patient hospital stays.

The investigator's goal is to improve the appropriateness of use of VTE prophylaxis among those in which the risks of harm may outweigh the benefit. Results from this study will provide important insights about use of risk assessment, and the relationship between patient mobility and VTE prophylaxis. These results are critical to understanding how to take the next steps toward improving the appropriate use and safety of anticoagulants in hospitalized older adults. Information from this study could be used in future proposals to study interventions to ultimately improve hospital practice in the care of older adults.

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Key information

Age range

60 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Duke University Medical Center

Durham, North Carolina, 27701, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age of 60 or older
  • Admitted to General Medicine at Duke University

Exclusion criteria

  • Clear contraindications to pharmacologic VTE prophylaxis
  • Receiving surgery during their index hospital stay
  • On observation admission status
  • On negative pressure room respiratory isolation
  • Wrist site is not available, i.e. wearing bilateral wrist IVs, skin breakdown at the time of screening
  • Ankle site is not available, i.e. patients with leg ulcer at the time of screening
  • Lacking decision-making ability (such as from severe cognitive impairment) and no LAR available
  • Non-English speakers

Treatment and study plan

Primary outcomes

  1. Total number of minutes of activity (using objective accelerometer data).

    Time frame: Length of hospital stay or up to 7 days during the patient's hospital stay.

  2. Total number of minutes of inactivity (using objective accelerometer data).

    Time frame: Length of hospital stay or up to 7 days during the patient's hospital stay.

Secondary outcomes

  1. Total number of steps (using objective accelerometer data).

    Time frame: Length of hospital stay or up to 7 days during the patient's hospital stay.

Sponsors and collaborators

Lead sponsor

Duke University

Other

Collaborators

  • Hartford Foundation
  • National Institute on Aging (NIA)
  • National Institutes of Health (NIH)
  • T. Franklin Williams Scholars

Registry information

Official study title

Adherence to Venous Thromboembolism Prophylaxis Guidelines in Hospitalized Elders

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Jan 19, 2017
Registry last updated
Nov 8, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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