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NCT Number: NCT06343597

Volume Outcome Relationships and Effects

This is a retrospective analysis to assess if high-volume hospital facilities experience greater or lesser rates of incidence in patients with esophageal cancer than low-volume facilities.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Methodist Richardson Medical Center

Richardson, Texas, 75082, United States

Location status: Recruiting

Location contact

Crystee Cooper, DHEd

CONTACT

[email protected]

2149471280

Dhiresh Jeyarajah, MD

PRINCIPAL_INVESTIGATOR

Zaid Haddadin, MS

CONTACT

[email protected]

2149471280

About this study

This is a retrospective analysis to assess if high-volume hospital facilities experience greater or lesser rates of incidence in patients with esophageal cancer than low-volume facilities.

The relationship between volume and outcomes has been proven in pancreatic cancer. Similar to pancreatic cancer, esophageal cancer historically has a bad prognosis. Esophageal cancer is typically asymptomatic, resulting in an advanced stage at the time of diagnosis. Additionally, it also has a significantly high morbidity and mortality. Therefore, it is crucial to determine volume-outcome relationships in esophageal cancer. This study aims to elucidate what these findings may entail by evaluating the impact that the volume-outcome relationship has on treatment assessment in esophageal cancer patients.

The purpose of the study is to evaluate the outcomes of esophageal cancer resection in patients in high volume (more than 5 esophagectomy performed per year) and low volume (less than 5 esophagectomy performed per year) hospital facilities. Furthermore, this paper will assess the outcomes of neoadjuvant and adjuvant therapy in esophageal cancer.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • esophageal cancer

Exclusion criteria

  • No esophageal cancer

Treatment and study plan

Primary outcomes

  1. Esophageal Cancer resection in patients in high volume (more than 5 esophagectomy performed per year) and low volume (less than 5 esophagectomy performed per year) hospital facilities

    Time frame: through study completion, up to 18 months

    Retrospective analysis to assess if high-volume hospital facilities experience greater or lesser rates of incidence in patients with Esophageal Cancer than low-volume facilities

Study contacts

Contact information is provided by the study sponsor or research team.

Crystee Cooper, DHEd

CONTACT

[email protected]

214-947-1280

Zaid Haddadin, MS

CONTACT

[email protected]

214-947-1280

Sponsors and collaborators

Lead sponsor

Methodist Health System

Other

Registry information

Official study title

Volume Outcome Relationships and Effects of Adjuvant and Neoadjuvant Therapy in Mortality in Esophageal Cancer

Important dates

Study start
2020
Primary completion
2027
Study completion
2028
First posted
Apr 2, 2024
Registry last updated
Mar 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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