Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography

3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.

Completed

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Key information

Conditions

Necrotic Pulp Dental Pulp Diseases Dental Pulp Necrosis Infections Necrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Periapical; Infection Stomatognathic Diseases Tooth Diseases

Age range

20 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Early Phase 1

Primary location

Alexandria University

Alexandria, Egypt

About this study

REPs were done for 10 mature maxillary necrotic teeth with periapical lesions confirmed by digital periapical radiographs. Instrumentation was done using Protaper Next till size X3 (size 30). Pre-operative radiographs also included CBCT scans to measure the 3D volume and area of the periapical lesion to be used as baseline data. The postoperative radiographic examination included: a) digital periapical radiographs taken at 3,6,9, and 12 months to monitor the lesion through out the follow-up period. b)CBCT scan to measure quantitatively the volume and area of the periapical lesion after 12 months follow up

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Necrotic Mature Maxillary anterior teeth with periapical lesions.

Exclusion criteria

Patients with mobile and fractured teeth

Treatment and study plan

Regenerative Endodontics Procedures (REPs)

Other

REPs was done for 10 mature maxillary necrotic teeth with periapical lesions. Instrumentation was done using Protaper Next system till size X3. Irrigation with 1.5 % NaOCl was done in the first visit. in the second visit, bleeding was induced in the canal by irritating the periapical area followed by the application of Biodentine as cervical plug then completion of the coronal restoration.

Primary outcomes

Measurement the volume of periapical lesion preoperatively and comparing it with the new volume after REPs using cone-beam computed tomography.

Time frame: 12 months

Measuring the volume in mm3

Sponsors and collaborators

Lead sponsor

Alexandria University

Other

Registry information

Official study title

3 D Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography

Important dates

Study start: 2017
Primary completion: 2018
Study completion: 2018
First posted: Nov 30, 2020
Registry last updated: Nov 30, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed