"Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail

To compare the renal protective properties of two currently used anaesthetic techniques - a sevoflurane-remifentanil/sufentanil combination with a propofol-remifentanil/sufentanil combination for anaesthesia in patients undergoing living donor kidney donation/transplantation.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Kidney Donation/Transplantation

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University Medical Center Groningen

Groningen, 9713 EZ, Netherlands

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All patients: Age > 18 years

Exclusion criteria

patient refusal
BMI< 17, >35
neurological disorder
recent use of psycho-active medication, including alcohol.
Donor-recipient couples from the ABO-incompatible program
Altruistic donor

Treatment and study plan

procedure:sevoflurane-remifentanil/sufentanil

Drug

Active Comparator

volatile agent only during reperfusion

Drug

Active Comparator

propofol-remifentanil/sufentanil

Drug

Active Comparator

Primary outcomes

To compare the renal protective properties of two currently used anaesthetic techniques

Time frame: participants will be followed for the duration of hospital stay

Sponsors and collaborators

Lead sponsor

University Medical Center Groningen

Other

Registry information

Important dates

Study start: 2010
Primary completion: 2012
Study completion: 2012
First posted: Nov 25, 2010
Registry last updated: Apr 18, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.