Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT05337514

Voice-Activated Technology to Improve Mobility in Multimorbid, Frail, Homebound Older Adults (EngAGE)

The purpose of this study is to test the efficacy of EngAGE (an interactive, voice-activated app) vs usual care on improving older adult physical and social function.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Notify Me

Key information

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Chicago

Chicago, Illinois, 60637, United States

About this study

Physical activity is essential for all age groups, across all comorbidities and geriatric syndromes; it has been described as the 'ideal' intervention for aging. Increasing physical activity among homebound, multimorbid, African American (AA) older adults (OAs) requires a shift in interventions to target the older adult-care partner (CP) pair (dyad) and to test innovative vehicles for remote intervention delivery. Our research goal is to create an evidence-based intervention that leverages technology to reach multimorbid OA-CP dyads in the home, promotes long-term mobility and social engagement among those least able to access community resources, and empowers informal care partners with tools. We developed a socially-motivated exercise tool for multimorbid OA-CP dyads called EngAGE that leverages voice-activated technology. We propose to conduct a 6-month, randomized, in-home trial of EngAGE (intervention) versus paper exercise handouts (usual care) in 124 multimorbid, homebound, AA OA-CP dyads recruited from 2 hospital systems and the community. Our overall hypothesis is that EngAGE will improve both physical and social function of older adults.

All OA subjects will undergo an in-home baseline visit where we will collect data about physical function, social function, activity and frailty. OA-CP dyads will be randomized (1:1) to a physical activity intervention: either EngAGE or usual care. All subjects will be asked to complete exercises 3-6 times per week. Care Partners will be instructed to encourage their Older Adult partner to perform physical activities on a regular basis. There is a two week Run-In Period to troubleshoot the EngAGE app and acclimate the OA subjects to the study intervention. OA subjects will be monitored via phone visits on a monthly basis. In home study visits will take place at month 3 and month 6. Data about OA subject physical function, social function, activity and frailty will be collected at these visits.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age greater than or equal to 60 years
  • has at least 2 chronic conditions
  • requires any assistance to leave the home (this may include requiring someone to drive, requiring the use of a cane or walker, or similar)
  • can read 14 point font from a 2-foot distance on a tablet-sized screen
  • can hear spoken voice from 2-foot distance
  • SPPB score of less than or equal to 9 but greater than 3 on a 12-point scale to target moderate but not severe functional impairment.

Exclusion criteria

  • reported history of moderate to advanced cognitive impairment;
  • inability to stand unassisted;
  • inability to understand English (because the intervention is currently only available in English);
  • life expectancy less than 12 months or enrolled in Hospice;
  • a medical condition making unsupervised physical activity potentially unsafe including: stroke within prior 12 months, acute myocardial infarction or unstable angina in the prior 6 months, uncontrolled arrhythmias, dissecting aortic aneurysm, acute endo/pericarditis, acute thromboembolism, acute or severe heart or respiratory failure, uncontrolled hypertension greater than 180/100, fracture or joint replacement within the prior 3 months, infections affecting one's general health condition, severe peripheral vascular disease.
  • severe functional impairment as indicated by an SPPB score less than 3 (out of 12);
  • baseline Montreal Cognitive Assessment of less than or equal to 18/30;
  • inability to understand consent (teach back).

Treatment and study plan

Enhanced Engagement

Behavioral

EngAGE will allow care partners send older adults encouragement which will be read aloud to the older adult through the EngAGE app.

Standard Engagement

Behavioral

Care partners can encourage their older adult partner using traditional / existing communication mechanisms.

Primary outcomes

  1. Timed Chair Stands

    Time frame: 6 months

    5 repeated chair stands

Secondary outcomes

  1. Grip Strength

    Time frame: 6 months

    Dominant grip strength measured with a dynamometer, average of 3 attempts

  2. Loneliness

    Time frame: 6 months

    Measured with the 9-item UCLS loneliness scale

  3. 4 meter usual walk

    Time frame: 6 months

    Participants walk 4 meters 2 times at their usual pace, fastest of 2 attempts.

  4. Static Balance Poses

    Time frame: 6 months

    Participants are asked to hold a side-by-side, semi-tandem and tandem balance pose each for 10 seconds.

  5. Physical activity

    Time frame: 6 months

    Wrist accelerometers will be worn for 7 full days in the free living environment.

Sponsors and collaborators

Lead sponsor

University of Chicago

Other

Collaborators

  • National Institute on Minority Health and Health Disparities (NIMHD)
  • National Opinion Research Center
  • Rush University

Registry information

Official study title

Voice-Activated Technology to Improve Mobility in Multimorbid, Frail, Homebound Older Adults: EngAGEing Older Adult-Care Partner Dyads

Acronym: EngAGE

Important dates

Study start
2022
Primary completion
2025
Study completion
2026
First posted
Apr 20, 2022
Registry last updated
May 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.