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NCT Number: NCT06114485

Voice Activated Personal Assistant for Depression Among Older Adults

Participants will use Amazon Alexa to test a new voice-assisted program for mental health management. The participant will use this program to help with goal setting, reminders, and various other services. The participant may be supported by a caregiver, if available, or by research team member who will serve as a coach for the duration of the study to guide them with using the program. Participants will be asked to complete surveys and assessments about their experiences during the 12-week study period. Participants will be randomized into two groups: those who receive a guide to help them with utilization of the program to its fullest potential and those who do not receive that guide.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Northwestern University

Chicago, Illinois, 60611, United States

About this study

Older adults have often been on the fringe of benefiting from technology. However, voice-controlled intelligent personal assistants (VIPAs; e.g. Google Home, Amazon Echo), with their natural interaction style and ease of use, are a simple interface technology that may be useful to older adults with depression in the home setting. The caregiver or coach will be able to schedule and follow the interactions between the older adult and the VIPA. The VIPAs would potentially be able to provide functional, cognitive, and social stimulation as well as improve anti-depressant medication adherence through reminders to older adults.

The aim is to evaluate a VIPA that was designed to deliver behavioral activation prompts to older adults with depression. Through user centered design (UCD), the investigators have adapted the model for remote support with the aid of VIPAs that provide psychoeducation, as well as features that support social, cognitive, and functional stimulation and reminders.

The intervention will be 8 weeks, with a 4-week follow-up. During 8-week intervention, participants will be able to use Amazon Echo Show 8 and the study's VIPA program to set goals, reminders, and the like to help with their mood. Participants will also be asked to completed associated assessments. If caregivers are involved, they will also be asked to complete assessments.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults 65 years or older
  • English-speaking
  • Elevated depressive symptoms (PHQ-9 ≥ 10)
  • Have Wi-Fi access
  • Cognitively intact (Montreal Cognitive Assessment (MOCA) score ≥17)

or

Inclusion criteria

  • Adults 18 years or older
  • English-speaking
  • Provide support to an older adult (65 or older)
  • Have access to Wi-Fi
  • Demonstrating capacity to consent
  • Cognitively intact (Montreal Cognitive Assessment (MOCA) score ≥17 if 65 years or older)

Treatment and study plan

VIPA Treatment Program

Behavioral

Participants will receive and Alexa device with a behavioral activation program, along with a detailed guidebook about how to utilize the Alexa device and the VIPA program

Alexa with Guidebook

Behavioral

Participants will receive an Alexa device with a detailed guidebook on how to use the device.

Primary outcomes

  1. Depressive symptoms

    Time frame: 12 weeks

    The Patient Health Questionnaire-9 (PHQ-9) PHQ-9 measures depression symptom severity on a scale of 0-27, with higher scores indicating greater symptom severity.

    The PHQ-9 measures depressive symptom severity on a scale of 0-27, with higher scores indicating greater severity

  2. Anxiety symptoms

    Time frame: 12 weeks

    The Generalized Anxiety Disorder-7 (GAD-7) measures anxiety symptom severity on a scale of 0-21, with higher scores indicating greater severity

Secondary outcomes

  1. Adherence

    Time frame: 8 weeks

    The number of times the Alexa device was accessed (Usage; # communications with TES-VIPA)

Sponsors and collaborators

Lead sponsor

Northwestern University

Other

Registry information

Official study title

Technology-Enabled Services to Support Caregivers of Older Adults With Depression

Important dates

Study start
2023
Primary completion
2025
Study completion
2026
First posted
Nov 2, 2023
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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