Vitamin D Supplementation in Vitamin Deficient Women Undergoing IVF Cycles: Does it Affect the Fertility Outcome?

The aim of this study is to evaluate the effect of treatment of vitamin D deficiency (through vitamin D supplementation for 8 weeks before the start of In-vitro fertilization (IVF) on the success of IVF cycles.

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Key information

Conditions

Infertility Genital Diseases Urogenital Diseases

Age range

20 year–35 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 4

Primary location

Department of Obstetrics and Gynecology, Kasr Al-Ainy hospital

Cairo, Greater Cairo, 11956, Egypt

About this study

The study participants are vitamin D deficient females undergoing (intra-cytoplasmic sperm injection (ICSI) trial in the age of 20 to 35 years. Serum vitamin D will be assessed. Accordingly, if they are deficient in vitamin D, they will be eligible for the study.400 vitamin D deficient women will be randomly allocated to either one of two groups. The first group will receive vitamin D supplementation in addition to the routine care. The other group will receive the routine care only. The study will be conducted in the IVF unit of department of Obstetrics and Gynecology, Cairo University.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Vitamin D deficient females undergoing first ICSI trial
Age from 20 to 35 years

Exclusion criteria

Women undergoing ICSI trials who are vitamin D sufficient

Treatment and study plan

Vitamin D

Drug

Vitamin D supplement will be given. Then, it will be maintained if pregnancy occurred

Other names: Calcitriol

Primary outcomes

Clinical pregnancy rate

Time frame: It will be calculated 1 year after enrollment of the first patient in the study

This outcome will be calculated by a statistician

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Vitamin D Supplementation in Vitamin Deficient Women Undergoing ICSI Cycles: Does it Affect the Fertility Outcome?

Important dates

Study start: 2017
Primary completion: 2021
Study completion: 2021
First posted: Jul 6, 2017
Registry last updated: Oct 6, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed