Vitamin D Levels and Survival in Cancer Patients

Using the population-based data sources in Iceland and the well-characterized AGES-Reykjavik cohort, our overarching aims are on exploring whether pre-diagnostic serum levels of 25-hydroxyvitamin D (25(OH)D) among older individuals living in Iceland were associated with survival after cancer diagnosis. We also wanted to assess the risk of being diagnosed with cancer in association with 25(OH)D levels. In this population living just south of the arctic circle, vitamin D levels largely depend on dietary- and supplemental sources.

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Key information

Conditions

Neoplasms

Age range

66 year–98 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

To be part of the AGES-Reykjavik Study, initiated between 2002 and 2006.

Exclusion criteria

Diagnosed with cancer at study entry

Treatment and study plan

Primary outcomes

Overall mortality among cancer patients

Time frame: Patients were followed from date of diagnosis since 2002 until death or censored at end of the follow-up (December 31, 2014)

We tested the association between pre-diagnostic 25(OH)D levels and total survival

Secondary outcomes

Cancer-specific mortality among cancer patients

Time frame: Patients were followed from date of diagnosis since 2002 until death or censored at end of the follow-up (December 31, 2014)

We tested the association between pre-diagnostic 25(OH)D levels and cancer survival

Other outcomes

Pre-diagnostic 25(OH)D levels and cancer risk

Time frame: Participants without cancer were followed from the study entry since 2002 until cancer diagnosis, death or end of the observation period whichever occurred first (December 31, 2014)

We tested the association between pre-diagnostic 25(OH)D levels and risk of being diagnosed with cancer

Sponsors and collaborators

Lead sponsor

Icelandic Heart Association

Other

Collaborators

University of Iceland

Registry information

Official study title

Association of Pre-diagnostic Vitamin D Levels and Survival in Older Individuals With Cancer

Important dates

Study start: 2002
Primary completion: 2006
Study completion: 2006
First posted: Aug 30, 2017
Registry last updated: Aug 30, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed