Visual Outcome After Transsphenoidal Surgery for Pituitary Macroadenoma

Endoscopic endonasal transsphenoidal surgery is a procedure for the treatment of pituitary macroadenomas that cause visual impairment through optic chiasm compression. The aim of this retrospective study is to describe visual outcome after this procedure.

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Key information

Conditions

Pituitary Tumor Brain Diseases Brain Neoplasms Central Nervous System Diseases Central Nervous System Neoplasms Endocrine Gland Neoplasms Endocrine System Diseases Hypothalamic Diseases Hypothalamic Neoplasms Neoplasms Neoplasms by Site Nervous System Diseases Nervous System Neoplasms Optic Chiasm Disorder Pituitary Diseases Pituitary Neoplasms Supratentorial Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Pituitary tumor causing optic chiasm compression (documented on MRI or CT-scan)
Visual impairment caused by chiasm compression
Treatment by transsphenoidal endonasal surgery
Treatment in the Rothschild Foundation (Paris) between 2009 and 2013

Exclusion criteria

Ophtalmologic condition other than optic chiasm compression

Treatment and study plan

Endonasal transsphenoidal pituitary tumor removal

Procedure

Removal of pituitary tumor by transsphenoidal endonasal surgery

Primary outcomes

Post-operative gain in visual acuity

Time frame: six months

Difference between pre-operative and post-operative visual acuity, expressed in LogMAR

Sponsors and collaborators

Lead sponsor

Fondation Ophtalmologique Adolphe de Rothschild

Network

Registry information

Acronym: RetroADEN

Important dates

Study start: 2015
Primary completion: 2016
Study completion: 2016
First posted: Dec 6, 2017
Registry last updated: Dec 6, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed