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OpenTrials
Completed

NCT Number: NCT01399073

Virtual Reality for Neglect Diagnostics

Compared to the classical "paper and pencil"-tests, testing patients in our virtual reality setup might have a higher sensitivity and specificity.

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Key information

Conditions

Spatial Neglect Blindness Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Eye Diseases Hemianopsia Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Sensation Disorders Signs and Symptoms Stroke Vascular Diseases Vision Disorders

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Charité University Medicine

Berlin, 10117, Germany

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

for neglect patients:

  • age ≥18 and <80 years
  • first stroke
  • neglect symptoms
  • no hemianopsia symptoms
  • consent given by the patient

Inclusion criteria

for hemianopsia patients:

  • age ≥18 and <80 years
  • first stroke
  • no neglect symptoms
  • hemianopsia symptoms
  • consent given by the patient

Inclusion criteria

for Controls:

  • age ≥18 and <80 years
  • no neurological deficits
  • informed consent

Exclusion criteria

(for all groups):

  • language comprehension deficits
  • motor deficits of the upper extremities
  • cognitive impairments (MMSE <20 or SKT >15 or DEMTEC >12)
  • depression
  • seizure disorders
  • claustrophobia

Treatment and study plan

virtual reality setup

Behavioral

testing for neglect in a virtual reality setup

paper and pencil tests

Behavioral

testing for neglect with the classical paper-and-pencil tests

c-mri

Other

structural and functional (resting state) imaging

Primary outcomes

  1. Feasibility

    Time frame: within the first 2 years after stroke

    Feasibility of the use of a virtual reality setup in the diagnostics of neglect

Secondary outcomes

  1. Sensitivity and Specificity

    Time frame: within the first 2 years after stroke

    The diagnostics of neglect via a virtual reality setup is more sensitive and more specific than the standard diagnostics via "paper-and-pencil" Tests

  2. mri (functional (resting state) and structural imaging

    Time frame: within the first 2 years after stroke

    We hypothesize that there are connectivity-based differences in the different stages of neglect and anatomical and functional connectivity correlates with respect to behavioural impairment.

Sponsors and collaborators

Lead sponsor

Charite University, Berlin, Germany

Other

Collaborators

  • Berlin Center for Advanced Neuroimaging
  • Freie Universität Berlin
  • Humboldt-Universität zu Berlin
  • Median Klinik Kladow
  • NeuroCure Clinical Research Center, Charite, Berlin

Registry information

Acronym: KMS-Neglect

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Jul 21, 2011
Registry last updated
Nov 29, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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