Skip to main content
OpenTrials
Completed

NCT Number: NCT05318703

Virtual Exercise For Older Adults With Mild Cognitive Impairment

This project is designed to develop and evaluate an Internet-based exercise intervention (tai ji quan Moving to Improve Brain Health) using real-time videoconferencing for older adults with mild cognitive impairment (MCI).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Mild Cognitive Impairment Cognition Disorders Cognitive Dysfunction Mental Disorders Neurocognitive Disorders

Age range

65 year–95 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Oregon Research Institute

Eugene, Oregon, 97403, United States

About this study

The project has three major goals: (a) transforming an in-person tai ji quan brain health intervention protocol into an online (virtual) class protocol and evaluating its feasibility of implementation in older adults with MCI, (b) developing and evaluating online assessment and data ascertainment procedures that encompass cognitive and physical performance measures, and (c) conducting a randomized controlled trial comparing the effectiveness of this new online intervention protocol with a conventional stretching exercise group in older adults with MCI.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Self-report a change or decline in memory (corroborated by an informant)
  • Record a score of ≤0.5 on the Clinical Dementia Rating (CDR) scale (with information derived from both the participant and an informant)
  • Show no major impairment in cognitive function as indexed by a score of ≥24 on the Mini Mental State Evaluation (MMSE).

Exclusion criteria

  • Have participated in a rigorous and structured physical activity or exercise program (including Tai Ji Quan) in the past 6 months,
  • Show major signs of depression as indicated by a score of ≥5 on the Geriatric Depression Scale
  • Have major medical or physical conditions that preclude exercise, as determined by their healthcare practitioner
  • Being unable to follow the consent process or sign the study consent form.

Treatment and study plan

tai ji quan

Behavioral

cognitively enhanced tai ji quan exercise

Stretching

Behavioral

Stretching exercise

Primary outcomes

  1. (a) Total number of intervention sessions taught by instructors over the course of study (recorded by a class check sheet) and (b) total number of classes attended by participants over the course of intervention as recorded by class attendance sheet

    Time frame: 16 weeks

    assess the extent to which interventionists successfully implement the prespecified exercise training protocol.

  2. number of dropouts from the intervention and study as assessed by a study recording sheet

    Time frame: 16 weeks

    assess intervention dropout rate and retention rate

  3. Number of participants expressing intervention program satisfaction as assessed by a self-report survey

    Time frame: 16 weeks

    assess the program acceptability among tai ji quan participants

  4. Change in global cognitive function assessed by Montreal Cognitive Assessment

    Time frame: baseline, 16 weeks

    assess change from baseline cognitive function at 16 weeks

  5. Change in attention and working memory as assessed by Digit Span - forward and backward

    Time frame: baseline, 16 weeks

    assess change from baseline in attention and working memory at 16 weeks

  6. Change in dual-task cost as assessed by Timed Up and Go with a cognitive task

    Time frame: baseline, 16 weeks

    assess change from baseline in the ability to stand up from a chair, walk, and sit down while performing an arithmetic task at 16 weeks

  7. Change in executive function as assessed by Trail Making B

    Time frame: baseline, 16 weeks

    assess change from baseline executive function at 16 weeks

  8. Change in executive function as assessed by Category Fluency for Animals

    Time frame: baseline, 16 weeks

    assess change from baseline executive function at 16 weeks

  9. Change in cognitive functioning assessed by Everyday Cognition

    Time frame: baseline, 16 weeks

    assess change from baseline cognitive functioning at 16 weeks

  10. Change in physical performance as measured by Timed Up and Go test

    Time frame: baseline, 16 weeks

    assess change from baseline in the ability to stand up from a chair, walk, and sit down at 16 weeks

  11. change in leg strength as assessed by 30-second chair stand test

    Time frame: baseline, 16 weeks

    assess change from baseline in leg strength at 16 weeks

  12. Change in balance using a 4-stage balance test

    Time frame: baseline, 16 weeks

    assess change from baseline in balance at 16 weeks

Secondary outcomes

  1. Change in depression as assessed by Geriatric Depression scale

    Time frame: baseline, 16 weeks

    assess change from baseline in the level of depression at 16 weeks

  2. Change in physical activity as assessed by International Physical Activity Questionnaire

    Time frame: baseline, 16 weeks

    assess change from baseline in physical activity at 16 weeks

  3. Change in quality of life as assessed by EuroQol (EQ-5D-3L)

    Time frame: baseline, 16 weeks

    assess change from baseline in quality of life at 16 weeks

Sponsors and collaborators

Lead sponsor

Oregon Research Institute

Other

Registry information

Official study title

Virtual Exercise Intervention for Older Adults With MCI

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Apr 8, 2022
Registry last updated
Mar 22, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.