NCT Number: NCT07373327
This study is investigating the effectiveness of two different types of wound dressings in treating diabetic foot ulcers (DFUs), a common complication of diabetes that can be difficult to heal. The study will compare the use of vinegar dressings to normal saline (saltwater) dressings to see which one helps heal the wound faster and more effectively.
People with diabetic foot ulcers often struggle with infections and slow healing. The goal of this study is to determine if vinegar, a simple and affordable treatment, works better than saline in improving wound healing and reducing infections. The study will measure how quickly the wound heals, how much dead tissue is removed, and whether the bacteria in the wound disappear.
This study will involve patients with infected diabetic foot ulcers. Participants will be randomly assigned to receive either vinegar or saline dressing. The results will help determine the best and most cost-effective treatment for diabetic foot ulcers, potentially making it easier for patients to access better care.
Trial opening soon.
Get Notified20 year–65 year
All sexes
Interventional
Not applicable
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
In this arm, participants will receive a dressing made by soaking gauze in a vinegar solution. The solution will be prepared by adding one tablespoon of plain white vinegar to a cup of normal saline. The gauze will be applied to the wound in a wet-to-dry manner, twice daily, until the wound is fully healed or cultured negative. The goal is to assess the effectiveness of vinegar in promoting wound healing, reducing infection, and removing necrotic tissue.
In this arm, participants will receive a dressing using normal saline (saltwater). The wound will be washed with normal saline and dressed in a wet-to-dry manner, twice daily, until the wound is fully healed or cultured negative. This arm will serve as the control group, with the goal of comparing the outcomes of saline dressing to vinegar dressing in terms of wound healing, bacterial infection reduction, and necrotic tissue removal.
Time frame: From enrollment to 8 weeks after treatment initiation
Definition: The proportion of participants whose wound cultures become negative (no bacterial growth) by the end of the treatment period (e.g., 3 weeks or 8 weeks).
Measurement: The swab cultures will be taken weekly, and the presence or absence of bacterial infection will be recorded until the wound is culture-negative.
Rationale: This outcome is crucial as it directly measures the effectiveness of vinegar dressing in reducing wound infection compared to normal saline dressing.
Contact information is provided by the study sponsor or research team.
University of Health Sciences Lahore
Other
A Randomized Clinical Trial to Compare the Efficacy of Vinegar Dressing Versus Normal Saline Dressing in the Treatment of Diabetic Foot Ulcers
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