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NCT Number: NCT05600140

Viewing Strategy Training in Children With (Cerebral) Visual Impairment

Viewing strategies are strategies used to process visual Information. Many children with visual impairment seem to lack systematic viewing strategies. However, it is unknown how viewing strategies differ between children with normal vision and children with (cerebral) visual impairment. In addition, viewing strategy training is often adopted in clinical practice, but till date there is no scientific evidence about effectiveness of this approach.

The current project has two goals: (1) to measure viewing strategies used by children with normal vision, children with ocular visual impairment and children with CVI, and (2) to evaluate whether training viewing strategies results in more efficiënt visual Information processing.

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Key information

Age range

5 year–12 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Royal Dutch Visio

Nijmegen, Netherlands

Location status: Recruiting

Location contact

Hanna Romema, MSc

CONTACT

Hanna Rozema, MSc

PRINCIPAL_INVESTIGATOR

CONTACT

[email protected]

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

typically developing children with normal vision:

  • Age 5-12 years
  • linear distant visual acuity of 0.1 logMAR or better
  • Verbal IQ above 70
  • Absence of developmental disorders or psychiatric problems like ASS or AD(H)D

Inclusion criteria

for children with ocular visual impairment:

  • Age 5-12 years
  • Children with linear distance visual acuity better <=1.3logMAR and >0.1 logMAR
  • Intact central visual field (at least > 30 degrees)
  • Children with a verbal IQ above 70
  • Absence of developmental disorders or psychiatric problems like ASS or AD(H)D

Inclusion criteria

for children with cerebral visual impairment:

  • Age 5-12 years
  • Linear distance visual acuity <=0.3 logMAR
  • Having the diagnosis CVI (verified by ophthalmologists)
  • Children with a verbal IQ above 70
  • Absence of psychiatric problems like ASS or AD(H)D

Additional inclusion criterion for study 2 (evaluating training effectiveness): children with (cerebral) visual impairment should have an indication for viewing strategy training. Training should not be indicated if children have no problems performing academic tasks (i.e. when speed and accuracy of visual processing is within the normal range). The age range for study 2 is 5-9 years.

Exclusion criteria

  • Children with VI: linear near visual acuity >1.0 logMAR
  • Children with visual field defect < 30 degrees
  • Children with a verbal IQ below 70
  • Children who attended a form of vision training in the past two years
  • Children with psychiatric problems like ASS or AD(H)D
  • Auditory impairment or language impairments
  • Major life events during training

Treatment and study plan

Viewing strategy training

Behavioral

Children receive a visual training of viewing strategies (six weeks, 2 times a week, 30 minutes). During the training, children are instructed to use specific viewing strategies (looking in a structured direction which fits the task at hand, zooming in and out / change of visual selective attentional field, visual discrimination). The verbal instructions and exercises are protocol-based. A textbook is used to describe the reactions of the children during training.

Primary outcomes

  1. Changes in reading accuracy after viewing strategy training

    Time frame: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4

    Radner reading test

  2. Changes in reading speed after viewing strategy training

    Time frame: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4

    Radner reading test

  3. Changes in visual search accuracy after training

    Time frame: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4

    Accuracy during conjunction search

  4. Changes in visual search speed after training

    Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4

    Speed during conjunction search

  5. Changes in saccade amplitudes during reading and visual search after training

    Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4

    Saccade amplitudes measured using Radner reading test and conjunction search

  6. Changes in fixation duration during reading and search after training

    Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4

    Fixation durations measured using Radner reading test and conjunction search

  7. Changes in average distance between fixation points during conjunction search (EB-VSA) after training

    Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4

    Average distance between fixation points using Radner reading test and conjunction search

Secondary outcomes

  1. Changes in WISC-V visual processing speed index (VSI) after training

    Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4

    WISC-IV visual processing speed index

  2. Changes in local visual selective attention after training

    Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4

    TEA-Ch Speurtocht (total number of symbols found in 1 minute)

  3. Changes in global visual selective attention after training

    Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4

    Gestalt Closure (Kaufman-ABC), number of correct answers

  4. Changes in visual identification speed after training

    Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4

    'DST-Plaatjes Benoemen', number of pictures correctly named within 1 minute

Study contacts

Contact information is provided by the study sponsor or research team.

Bianca Huurneman, PhD

CONTACT

[email protected]

0(031)646944002

Sponsors and collaborators

Lead sponsor

Royal Dutch Visio

Other

Collaborators

  • Radboud University, Behavioural Science Institute, Nijmegen, The Netherlands

Registry information

Official study title

Viewing Strategy Training in Children With (Cerebral) Visual Impairment: From Spontaneous Eye Movements to a Structured Viewing Strategy

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Oct 31, 2022
Registry last updated
Jan 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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