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OpenTrials
Completed

NCT Number: NCT07228507

Video Intervention of Relative Energy Deficiency in Sport

The Female and Male Athlete Triad (Triad) and Relative Energy Deficiency in Sport (REDs) are multifactorial conditions often under-recognized by healthcare professionals. Improving provider awareness is essential for early detection and multidisciplinary management in sport medicine. Thus, the objective was to assess the effectiveness of a brief online educational video in improving knowledge, attitudes, and perceived confidence toward the Triad and REDs among Spanish healthcare professionals.

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universidad del Pais Vasco

Leioa, Basque Country, 48940, Spain

About this study

The objective was to assess the effectiveness of a brief online educational video in improving knowledge, attitudes, and perceived confidence toward the Triad and REDs among Spanish healthcare professionals.

Design: Randomized controlled educational trial. A total of 200 Spanish healthcare professionals (physicians, nurses, and physiotherapists) were randomized 1:1 into an intervention group (VG) and a control group (CG). The VG received access to an 18-minute YouTube-based educational video titled "Triad of the Female Athlete and RED-S". The CG did not have access to the video until the study was completed. Both completed a validated 16-question questionnaire before and after the intervention.

The Primary Outcome Measure was the change in knowledge score about the Female/Male Athlete Triad and REDs. Secondary outcomes included questions from the definition group (questions 1 and 3), low energy availability group (questions 2, 4, 5, 10, 14, 15 and 16), the menstrual health group (questions 6,9,11 and 13) and the bone health group (questions 7,8 and 12)

Descriptive analyses were conducted to determine means, standard deviations, frequencies, and percentages. A two-way repeated-measures ANOVA was performed after verifying the statistical assumptions required for this methodology. Outliers were examined using the first and third quartiles and the interquartile range. Participants with a total score ≤4 were excluded from the analysis to preserve the reliability and validity of the data and to ensure that statistical analyses reflected only responses with adequate informational content consistent with the study conditions. Data normality was assessed through Q-Q plots and the Shapiro-Wilk test. The effects of the group factor (VG vs. CG), the time factor (pre- vs. post-test), and their interaction were analysed, considering a 95% confidence interval (p ≤ 0.05).

Knowledge Questions

  • What do you consider to be the three components of the Female Athlete Triad?
  • Low energy availability in a person occurs when the energy to maintain the functions required by the human body to preserve health and optimal performance is insufficient.
  • What is the main factor that would cause REDs?
  • Low energy availability could be associated with a decrease in carbohydrate intake.
  • There may be low energy availability without changes in weight or body mass index.
  • Menarche in adolescents after the age of 15 is normal if they engage in intense physical activity.
  • At what age does peak bone mineral density occur in women?
  • Osteopenia in adolescent girls or young adult women can be reversed if, in adulthood, they reduce the intensity or volume of their physical activity.
  • In a physically active woman, secondary amenorrhea can be considered normal if she engages in intense sport.
  • Menstrual disorders in physically active women are a risk factor for having low bone mineral density.
  • Low energy availability can cause secondary amenorrhea in physically active women.
  • In physically active women, menstrual cycle alterations or amenorrhea are indicators of intense training.
  • In physically active women, stress fractures may occur at a higher rate in women with prolonged amenorrhea than in eumenorrheic women.
  • Low energy availability can affect an athlete's recovery.
  • Low energy availability can increase performance (strength, speed, power).
  • After performing intense exercise, the basis of caloric intake should be...

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Registered in a health professional association in Spain (medicine, nursing, or physiotherapy).
  • Voluntary participation and completion of the baseline questionnaire.
  • Consent to provide an email address for communication and randomization

Exclusion criteria

  • Not to be registered in a health professional association in Spain (medicine, nursing, or physiotherapy).
  • Incomplete questionnaire responses.
  • Total score ≤4 in the pre-test, to preserve data reliability and validity.

Treatment and study plan

Behavioral: Educational Program on Female Athlete Triad and Relative Energy Deficiency in Sport (RED-S)

Other

Participants in the intervention arm attended an educational session designed to improve knowledge about the Female Athlete Triad and REDs, focusing on definition, low energy availability, menstrual function, and bone health.

Primary outcomes

  1. Change in knowledge score (mean proportion of correct answers) from baseline to post-intervention.

    Time frame: Baseline and 4 weeks after intervention

    Knowledge assessed using a 16-item questionnaire on the Female Athlete Triad and Relative Energy Deficiency in sport. Each item scored 0-1 and the outcome is a score 0-16 points. A higher scores means better knowledge.

Secondary outcomes

  1. Change in definition questions group

    Time frame: Baseline and 4 weeks after intervention

    Correct answers from the definition questions group. Each question is scored 0-1 and the outcome is a score 0-2 points. A higher scores indicate greater knowledge.

  2. Change in low energy availability questions group

    Time frame: Baseline and 4 weeks after intervention

    Correct answers from the low energy availability questions group. Each question is scored 0-1 and the outcome is a score 0-7 points A higher scores indicate greater knowledge.

  3. Change in menstrual questions group

    Time frame: Baseline and 4 weeks after intervention

    Correct answers from the menstrual questions group. Each question is scored 0-1 and the outcome is a score 0-4 points. A higher scores indicate greater knowledge.

  4. Change in bone health questions group

    Time frame: Baseline and 4 weeks after intervention

    Correct answers from the bone questions group. Each question is scored 0-1 and the outcome is a score 0-3 points. A higher scores indicate greater knowledge.

Sponsors and collaborators

Lead sponsor

University of the Basque Country (UPV/EHU)

Other

Registry information

Official study title

Video-based Educational Intervention on Healthcare Professionals' Knowledge of Relative Energy Deficiency in Sport

Acronym: Video_REDs

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Nov 14, 2025
Registry last updated
Nov 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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