Video-EEG Features of Adult Patients With Psychogenic Nonepileptic Seizures

This completed retrospective observational study evaluated adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent video-EEG monitoring. Video-EEG records and clinical data of 50 adult patients were reviewed to describe semiological, electroclinical, and demographic characteristics of PNES. The study aimed to improve the understanding of video-EEG findings in PNES and to support accurate diagnosis in clinical practice.

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Key information

Conditions

Psychogenic Nonepileptic Seizures Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Seizures Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Saglik Bilimleri University Izmir Faculty of Medicine Department of Neurology

Izmir, Turkey (Türkiye)

About this study

Psychogenic nonepileptic seizures (PNES) are paroxysmal events that resemble epileptic seizures but are not associated with ictal epileptiform activity on EEG. Video-EEG monitoring is considered the reference standard for diagnosis. In this retrospective observational study, video-EEG recordings and clinical files of 50 adult patients with PNES were reviewed after completion of clinical care. Demographic data, clinical presentation, and video-EEG characteristics were analyzed descriptively. No intervention was assigned as part of the study. The purpose was to characterize the video-EEG and clinical profile of adult PNES patients evaluated in routine practice.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults aged 18 years and older

Diagnosis of psychogenic nonepileptic seizures based on video-EEG evaluation

Availability of complete video-EEG recordings and relevant clinical records for review

Exclusion criteria

Patients younger than 18 years

Inadequate or incomplete video-EEG data

Patients with insufficient clinical documentation for retrospective evaluation

Treatment and study plan

Primary outcomes

Semiological subtype of PNES events

Time frame: Baseline retrospective chart and video-EEG review

Classification of PNES events recorded during video-EEG monitoring into semiological clusters (pauci-kinetic, hyperkinetic, hyperventilation-eye closure) based on ictal features.

Secondary outcomes

Presence/absence of some events during PNES events

Time frame: Baseline

Eye closure during PNES events Hyperventilation during PNES events Hyperkinetic motor activity Axial extension Pelvic thrusting

Sponsors and collaborators

Lead sponsor

Saglik Bilimleri Universitesi

Other

Registry information

Official study title

Retrospective Analysis of Video-EEG Findings and Clinical Characteristics in Adult Patients With Psychogenic Nonepileptic Seizures

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2026
First posted: Apr 13, 2026
Registry last updated: Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed