Skip to main content
OpenTrials
Completed

NCT Number: NCT07210073

Video Education to Improve Blood Pressure Control in Patients With Ischemic Heart Disease and Hypertension (V-EDUCATE)

We investigated whether video-based education using deepfake technology could improve blood pressure measurement adherence and medication adherence in patients with ischemic heart disease accompanied by hypertension.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hypertension (HTN) Cardiovascular Diseases Heart Diseases Hypertension Ischemic Heart Disease Myocardial Ischemia Vascular Diseases

Age range

19 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Keimyung University Dongsan Hospital

Daegu, 42601, South Korea

About this study

Hypertension is a major risk factor for recurrent cardiovascular events in patients with ischemic heart disease, yet adherence to home blood pressure monitoring and prescribed medications remains suboptimal. Personalized and engaging educational strategies may help to improve adherence behaviors in this population.

This randomized controlled trial investigates the effectiveness of a video-based educational program, developed with deepfake technology, to deliver individualized health information. Participants are randomly assigned to either the intervention group, which receives the video education in addition to usual care, or the control group, which receives usual care alone.

The primary outcomes are adherence to home blood pressure monitoring and medication adherence after one month. Secondary outcomes include changes in office and home blood pressure, as well as 24-hour ambulatory blood pressure monitoring. The results of this study may provide evidence for scalable, technology-assisted strategies to enhance adherence and improve blood pressure control in high-risk cardiovascular patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 19 years or older, both male and female, with a history of hypertension or who have taken antihypertensive medication at least once, satisfying one or more of the following ischemic heart disease conditions (PCI, CABG, CAD >50% by CCT or CAG), or patients with a history of hypertension or currently taking antihypertensive medication.
  • Individuals who have voluntarily provided written consent to participate in this clinical trial.

Exclusion criteria

  • SBP < 90 mmHg or DBP < 50 mmHg
  • Individuals intolerant to all antihypertensive medications
  • Patients with heart failure due to other causes, Pregnant women, those suspected of being pregnant, or those who are breastfeeding
  • Patients whom the investigator deems legally or mentally unfit to participate in the clinical trial
  • Patients who have participated in another clinical study involving investigational drugs within 4 weeks prior to screening.

Treatment and study plan

Video Education

Behavioral

Videos were created using deepfake technology, utilizing AI to replicate the voice of the patients' primary physician.

Control

Other

Standard treatment

Primary outcomes

  1. Adherence to Home Blood Pressure Monitoring (HBPM)

    Time frame: 4 weeks

    Proportion of days during the 30-day follow-up period in which participants recorded four BP measurements per day (two in the morning, two in the evening) using a validated home BP device (InBody BP170).

  2. Medication Adherence Assessed by Pill Count

    Time frame: 4 weeks

    Proportion of prescribed antihypertensive medication doses taken during the 30-day follow-up period, assessed by pill counts at the follow-up visit.

Secondary outcomes

  1. Change in Office Systolic Blood Pressure From Baseline to 4 Weeks

    Time frame: 4 weeks

    Mean change in systolic blood pressure (SBP) measured in clinic using a standardized sphygmomanometer at baseline and 4 weeks.

  2. Change in Office Diastolic Blood Pressure From Baseline to 4 Weeks

    Time frame: 4 weeks

    Mean change in diastolic blood pressure (DBP) measured in clinic using a standardized sphygmomanometer at baseline and 4 weeks.

  3. Difference in Mean Systolic Blood Pressure Between Home BP Monitoring and 24-Hour Ambulatory Monitoring

    Time frame: 4 weeks

    Difference between mean SBP values obtained from home BP monitoring (HBPM) and 24-hour ambulatory BP monitoring (ABPM).

  4. Difference in Mean Diastolic Blood Pressure Between Home BP Monitoring and 24-Hour Ambulatory Monitoring

    Time frame: 4 weeks

    Difference between mean DBP values obtained from HBPM and ABPM.

  5. Number of Antihypertensive Medications Prescribed Per Participant

    Time frame: 4 weeks

    Total number of prescribed antihypertensive medications per participant at baseline and at 4 weeks.

  6. Distribution of Antihypertensive Medication Classes Used

    Time frame: 4 weeks

    Proportion of participants prescribed each class of antihypertensive medication (RAAS inhibitors, beta-blockers, calcium channel blockers, diuretics, etc.) at baseline and 4 weeks.

Sponsors and collaborators

Lead sponsor

Keimyung University Dongsan Medical Center

Other

Registry information

Official study title

Video Assisted Education to Improve Blood Pressure Control in Ischemic Heart Disease Patients With Hypertension: Randomized Controlled Trial

Acronym: V-EDUCATE

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Oct 7, 2025
Registry last updated
Oct 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.