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NCT Number: NCT07467005

Video Double-Lumen Tube for Secondary Pulmonary Resection

During thoracic surgery, double-lumen endotracheal intubation with one-lung ventilation is routinely performed to optimize surgical exposure, facilitate operative manipulation, and prevent iatrogenic lung injury. In patients undergoing repeat pulmonary surgery, prior lung resection may lead to pleural adhesions and tracheobronchial distortion, which substantially increase the difficulty of bronchial intubation. Even with experienced operators, the malposition rate of conventional double-lumen tubes remains high. The video double-lumen tube enables continuous visualization of the trachea and carina during insertion, positioning, and one-lung ventilation, allowing real-time airway monitoring. However, no clinical studies have specifically investigated airway management in patients undergoing redo pulmonary surgery. This study aimed to evaluate the efficacy and safety of the video double-lumen tube during anesthesia in patients undergoing secondary pulmonary resection.

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Key information

Conditions

Lung Cancer Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Pulmonary Nodule Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥18 years.
  • History of previous pulmonary resection.
  • Scheduled for elective pulmonary surgery.
  • Planned to receive a left-sided double-lumen tube.
  • ASA physical status I-III.
  • Patients have signed the informed consent form.

Exclusion criteria

  • Preoperatively predicted difficult airway (Mallampati ≥ III, Cormack-Lehane ≥ III).
  • Acute respiratory distress syndrome (ARDS) or respiratory failure within the past 3 months.
  • Uncontrolled asthma.
  • Confirmed pregnancy or current breastfeeding.
  • Multiple traumatic injuries.
  • Current participation in another clinical trial.
  • Other conditions deemed unsuitable by the investigator.

Treatment and study plan

Video Double-Lumen Tube Group

Device

Use the video double-lumen tube to perform left bronchial intubation under real-time visualization and continuously monitor its position.

Conventional Double-Lumen Tube Group

Device

Insert a conventional left-sided double-lumen tube using standard intubation techniques.

Primary outcomes

  1. Success rate of first-attempt bronchial intubation

    Time frame: During the first intubation attempt

Secondary outcomes

  1. Intubation time

    Time frame: Measured from insertion of the video laryngoscope into the mouth until confirmation of correct tube position

  2. Requirement for and number of fiberoptic bronchoscopy uses

    Time frame: During the entire intraoperative period

  3. Frequency of intraoperative tube repositioning

    Time frame: During the entire intraoperative period

  4. Surgeon's rating of lung collapse quality

    Time frame: During the entire intraoperative period

  5. Incidence of difficult intubation

    Time frame: At the time of intubation

  6. Intubation-related adverse events

    Time frame: From the start of intubation until 24 hours postoperatively

Other outcomes

  1. Incidence of intraoperative hypoxemia

    Time frame: During the entire intraoperative period

Study contacts

Contact information is provided by the study sponsor or research team.

Diansan Su

CONTACT

[email protected]

+86 18616514088

Sponsors and collaborators

Lead sponsor

Zhejiang University

Other

Registry information

Official study title

Video Double-Lumen Tube for Secondary Pulmonary Resection: A Multicenter Randomized Controlled Trial

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Mar 12, 2026
Registry last updated
Mar 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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