Vibrotactile Coordinated Reset for Spasticity After Spinal Cord Injury

Inclusion criteria

• Age at the time of enrollment: Any adult ages 18 and over
• Spinal Cord Injury: ASIA C or D injury at level C1-T1
• Duration of incomplete spinal cord injury minimum 1 years clinical/fundamental
• Spasticity with a of MAS score >3 present in upper extremities.
• Fluent in English
• If patient is on medication that affects brain function or alters EEG activity, the patient must feel comfortable going off this medication prior to EEG recording.
• Appropriate social support if required during an off-medication state.
• Comfortable with technology; can use a computer, check email, and access the internet; can initiate and engage in a virtual meeting for training and monitoring purposes.
• Feels comfortable going off certain spasticity related medication during in-person study visits
• Lives in the United States

Exclusion criteria

• Sensory deficits in palma manus resulting in missing inter digit discrimination of the fingertips.
• Any significant neuro-psychiatric problems, including acute confusional state, ongoing psychosis, or suicidal tendencies.
• Any current drug or alcohol abuse.
• Participation in another drug, device, or biologics trial concurrently or within the preceding 30 days. Any other trial participation should be approved by the Principal Investigators.
• Pregnancy, breast-feeding or wanting to become pregnant.
• Physical limitations unrelated to spasticity that would affect motor ratings.
• Craniotomy
• Brain surgery
• Patient is unable to communicate properly with staff (i.e., severe speech problems)
• Medications that may affect relevant synaptic plasticity
• Concurrent Botox treatment
• A type of hairstyle that would impede the use of an EEG cap.