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OpenTrials
Completed

NCT Number: NCT06500897

VEST Device to Enhance Safein Vein Patency

Purpose - Bypass grafting is the gold standard for severe coronary disease, yet most repeat revascularizations target previously grafted territories. External stenting of saphenous vein grafts, the most frequently used bypass conduit, has been shown to minimize disease markers. This study evaluates clinical outcomes of external stenting in real world routine practice.

Methods - Three centers enrolled a prospective real-world cohort of external- stenting- enhanced CABG patients. All patients received an internal mammary artery graft to the left anterior descending artery and additional arterial and/or venous grafts. One or more venous grafts were externally stented. Choice of conduits, use of cardiopulmonary bypass, and vein harvesting technique were performed according to the routine practice of each surgeon.

All patients were prescribed standard of care medication and were followed via on site visits or phone interviews for major adverse myocardial and cerebral effects.

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Medical University of Vienna, Vienna, Austria

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • CABG with at least one VEST implant

Exclusion criteria

  • none

Treatment and study plan

VEST

Device

External MEsh Support for safein vein

Primary outcomes

  1. Re-rivascularization

    Time frame: Up to 7 years

    Number of PCI or re-CABG performed, stratified by target site

  2. MACCE

    Time frame: Up to 7 years

    Major adverse cardiac and cerebrovascular events

Sponsors and collaborators

Lead sponsor

Cardiochirurgia E.H.

Other

Registry information

Official study title

Mid Term Follow up of VEST Device to Enhance Safein Vein Patency: a Multicentric Study

Important dates

Study start
2017
Primary completion
2024
Study completion
2024
First posted
Jul 15, 2024
Registry last updated
Jul 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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