Active, Not Recruiting

NCT Number: NCT06815848

Venous Drainage of the Craniocervical Junction: a Retrospective Anatomical Study (SVCR MR1)

This study aims to examine the feasibility of distinctly visualizing the different cervical venous networks (subcutaneous, muscular, extra-canalicular, and intra-canalicular) using dedicated magnetic resonance imaging (MRI) sequences. Theoretically, these venous networks contribute to the complex distribution of blood drainage in the cervical region, but their precise identification on imaging remains challenging.The objectives of this research are twofold: first, to assess the ability of MRI to differentiate each venous network, thereby enhancing the anatomical and functional understanding of this region; and second, to explore the possibility of grouping patients according to the predominant venous network, which could reveal significant physiological variations and specific anatomical profiles.The results could not only refine the diagnosis of cervical vascular pathologies but also guide targeted therapeutic approaches.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Notify Me

Key information

Conditions

Study of Venous Drainage of the Cranio-Cervical Junction Using MRI

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Chu Brest

Brest, 29609, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patient affiliated with a social security system
Age >18 years
Patient who underwent a T1 Angio-MRI with gradient echo and contrast agent of the cranio-cervical region, regardless of the indication, at the Brest University Hospital between 01/01/2019 and 01/11/2024

Exclusion criteria

Patients under judicial protection (guardianship, curatorship, etc.) Refusal to participate (expressed opposition) History of venous occlusive pathology OR vascular pathology such as cerebral or spinal AVM/FAV History of posterior cranial fossa surgery OR surgical approach to the posterior cervical spine History of radiotherapy/chemotherapy/any known vein-toxic therapies

Treatment and study plan

Primary outcomes

Number of venous vessel in the four venous networks (subcutaneous, muscular, extra-canal, and intra-canal).

Time frame: at the time of inclusion

Determine, for each patient, which cervical venous network is dominant and identify whether each patient exhibits all four venous networks (subcutaneous, muscular, extra-canal, and intra-canal).

Secondary outcomes

Number of vessel in each groups

Time frame: at the time of inclusion

Assess the relative significance of each identified venous network.
number of vessel on the left and the right in one patient

Time frame: at the time of inclusion

Examine whether there is a dominance of venous drainage on the right or left side in the same patient

Sponsors and collaborators

Lead sponsor

University Hospital, Brest

Other

Registry information

Official study title

Venous Drainage of the Craniocervical Junction: a Retrospective Anatomical Study

Acronym: SVCR MR1

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Feb 10, 2025
Registry last updated: Feb 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.