Urology and nephrology center
Al Mansurah, DK, 35516, Egypt
NCT Number: NCT03494049
Postoperative transient stress urine leakage following Holmium laser enucleation of the prostate is one of the problems that frustrate both surgeon and patients
Standard HoLEP might be associated with some stretch of the sphincter and de-epithelization of the sphincter area anteriorly.
In Veil preserving HoLEP, early separation of the adenoma from the sphincter ring minimizes sphincter stretch. Furthermore, more proximal incision of the 12 O'clock mucosal strip sparring a veil of mucosa covering the sphincter ring.
Our hypothesis is that by this technique the early postoperative transient urine leak would be minimized and duration of leakage if anny would be shortened.
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Notify Me50 year and older
Male
Interventional
Not applicable
Al Mansurah, DK, 35516, Egypt
Postoperative transient stress urine leakage following Holmium laser enucleation of the prostate is one of the problems that frustrate both surgeon and patients.
Many reports addressed different variables for the cause of post HoLEP urine leakage. Looking for a procedure done by a single surgeon who had tremendous experience of this procedure may enable investigators to identify precisely technical points of interest that may affect post HoLEP stress urine incontinence.
Standard HoLEP might be associated with some stretch of the sphincter and de-epithelization of the sphincter area anteriorly.
In Veil preserving HoLEP, early separation of the adenoma from the sphincter ring minimizes sphincter stretch. Furthermore, more proximal incision of the 12 O'clock mucosal strip sparring a veil of mucosa covering the sphincter ring.
Investigators' hypothesis is that by this technique the early postoperative transient urine leak would be minimized and duration of leakage if any would be shortened.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Patients who have any of the following were excluded:
Early mucosal incision; lateral to the Veru and proximal to the apical bulge of the adenoma, followed by early separation of the adenoma from the sphincter ring after identification of the plane of enucleation, this minimizes sphincter stretch.
Furthermore, more proximal incision of the 12 O'clock mucosal strip sparring a veil of mucosa covering the sphincter ring.
Other names: early apical separation
Holmium laser enucleation of the prostate in the standard approach described by Elhilali et al 2010
Time frame: 1 month postoperative
one hour pad test for post prostatectomy incontinence, scale from 0 to 4, the higher the more incontinence
Time frame: 1 year
Symptoms core assessment, score from 0 to 35, the higher the worse the urinary symptoms
Time frame: 1 year
rate of urine flow per unit time, how many milliliters of urine passed per second, above 15ml/second is normal
Time frame: 4 months postoperative
one hour pad test for post prostatectomy incontinence, scale from 0 to 4, the higher the more incontinence
Time frame: one month postoperative
Continence core assessment, score from 0 to 21, the higher the worse the urinary continence
Mansoura University
Other
Veil-preserving Versus Standard Holmium Laser Enucleation of the Prostate: Randomized Clinical Trial
Acronym: MansprostIV
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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