Vasopressin Deficiency in Hemorrhagic Shock

This is a prospective observational study. The only research-driven procedure will be the removal of blood samples at designated time points(total blood removed 48 cc per patient). Hemodynamic, fluid infusion and agitation/pain data (RAMSEY Score) will prospectively be collected for research purposes. We will collect data from a convenience sample of patients (when research staff is available) over a one year period.

Inclusion criteria

• Patient is a male or female patient presumed to be at least 18 years of age;
• Patient has a reported or actual systolic blood pressure < 90 mmHg within 1 hour of arrival to the Emergency Room;
• Patient has clinical evidence of acute traumatic injury;

Exclusion criteria

• Patient is asystolic or requires CPR prior to arrival;
• Patient was transferred from an outside facility
• Patient known to be pregnant
• Patient known to be prisoner