Vascular Health and Exercise Performance of Overweight Children

The purpose of this study is to assess exercise performance in 20 healthy children 10-19 years of age with a body mass index greater than 85th percentile and to evaluate the effect of dietary and exercise intervention over 12 weeks.

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Key information

Conditions

Patient Compliance Behavior Health Behavior Patient Acceptance of Health Care Treatment Adherence and Compliance

Age range

10 year–19 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Lucile Packard Children's Hospital at Stanford

Palo Alto, California, 94306, United States

About this study

Our hypothesis is that the vascular health in these children will improve at the end of intervention. The results of this study will help us in our long-term objective of improving vascular health of children with congenital/acquired heart disease, a group particularly at risk for premature atherosclerosis.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

10-19 years old
Overweight (BMI > 85 percentile)
Interested in a 12 week ¬home exercise & nutrition program
Have computer & internet access
Can come to Lucile Packard Children's Hospital at Stanford for a 3-hour test at the start & end of the study (so only twice!)
Are able to come to testing after fasting overnight
Do not smoke
Do not take any medications

Exclusion criteria

non-overweight adolescents

Treatment and study plan

Diet and Exercise Intervention

Other

Remote Dietary and Exercise Intervention Program

Primary outcomes

Vascular Health

Time frame: Beginning of 12th week and end of 12th week

Tests will include: EndoPAT analysis to assess endothelial function, applanation tonometry to assess arterial stiffness, carotid artery imaging to assess the wall thickness of the carotid arteries, exercise testing to assess the physical exercise capacity of these children and blood work to evaluate the lipid profile and inflammation status (CRP). The participant will be asked to come in after an overnight fast. They will receive a snack bag before the exercise test.

Sponsors and collaborators

Lead sponsor

Stanford University

Other

Registry information

Official study title

Vascular Health and Exercise Performance of Overweight Children in 12 Weeks Using Skype

Acronym: VHEPOC

Important dates

Study start: 2012
Primary completion: 2014
Study completion: 2014
First posted: Nov 20, 2012
Registry last updated: Oct 6, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed