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OpenTrials
Completed

NCT Number: NCT01213940

Vascular Endothelium Changes After Bariatric Surgery (Endothelial Progenitor Cells)

Improvement in cardiovascular mortality is related to changes in pathologic autoantibodies and in the number of circulating functional replicative competent endothelial progenitor cells (EPC's) after bariatric surgery.

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Key information

Conditions

Type 2 Diabetes Diabetes Mellitus Diabetes Mellitus, Type 2 Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases

Age range

19 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of South Alabama

Mobile, Alabama, 36617, United States

About this study

Same as above

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Type 2 Diabetes, Glucose > 200mg/dl, currently be ing treated with oral medications and HGA1c . 6.5, and BMI .35.

Exclusion criteria

  • Type 1 Diabetes

Treatment and study plan

pre-bariatric weight loss program

Behavioral

standard 6 month physician directed pre-bariatric weight loss program

Other names: weight loss program

bariatric surgery

Procedure

bariatric surgery for weight loss

Primary outcomes

  1. Change in Late Outgrowth Endothelial Progenitor Colonies

    Time frame: 24 months

    Primary outcome is the change in Late outgrowth endothelial progenitor colonies 12 months after enrollment to surgery (LRYGB) or to standard medical therapy (SMT).

Sponsors and collaborators

Lead sponsor

University of South Alabama

Other

Collaborators

  • American Society for Metabolic and Bariatric Surgery

Registry information

Official study title

Vascular Endothelium Changes After Bariatric Surgery

Acronym: EPC

Important dates

Study start
2010
Primary completion
2014
Study completion
2014
First posted
Oct 4, 2010
Registry last updated
May 9, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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