Vanguard Complete Knee Versus Vanguard High Flex Rotating Platform (RP) Knee Study

The primary objectives of this clinical study include:

• Evaluate size fit and long term performance of Vanguard Complete Knee ("Fixed") System in Asian and Latino population in comparison to competitor's similar product.
• Evaluate efficacy of Vanguard Complete Knee with Microplasty Tibial Tray.
• Compare Vanguard High Flex Rotating Platform ("High Flex") Knee System to Vanguard Complete Knee System in Asian population in terms of:

• Early ROM
• Clinical outcomes
• Kinetic and Kinematic characteristics in relation to Healthy Knees. o
• Compare current design to new design of Vanguard High Flex Rotating Platform Knee System in terms of :

• Early ROM
• Clinical outcomes
• Kinetic and Kinematic characteristics

Inclusion criteria

• Painful and disabled knee joint resulting form osteoarthritis, rheumatoid arthritis, traumatic arthritis where one or more compartments are involved.
• Correction of varus, valgus, or posttraumatic deformity.
• Correction or revision of unsuccessful osteotomy, or arthrodesis.
• Need to obtain pain relief and improve function.
• Ability and willingness of the patient to follow instructions, including control of weight and activity level.
• Good nutritional state of the patient.
• Patient must have reached full skeletal maturity.

Exclusion criteria

• Infection, sepsis, osteomyelitis, and failure of previous joint replacement.
• Uncooperative patient or patients with neurologic disorders who are incapable of following directions.
• Osteoporosis
• Metabolic disorders which may impair bone formation
• Osteomalacia
• Distant foci of infections which may spread to the implant site
• Rapid joint destruction, marked bone loss or bone resorption apparent on roentgenogram
• Vascular insufficiency, muscular atrophy, neuromuscular disease
• Incomplete or deficient soft tissue surrounding the knee