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NCT Number: NCT07497464

Validity of an Open-access Handedness Recognition Task in Stroke Patients

This study aims to assess the validity of a hand laterality discrimination task in patients who have suffered a stroke. The protocol involves two assessment sessions consisting of a Single Reaction Time (SRT) task and a Hand Laterality Judgement Task (HLJT). In the HLJT, participants are presented with images of right or left hands at various degrees of rotation and must determine the laterality of each hand. Primary outcomes include reaction time for the SRT, and both accuracy (percentage of correct responses) and decision-making time for the HLJT. Additionally, motor and kinesthetic imagery scales, as well as demographic and cognitive variables, are recorded.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Neuron Clinics

Madrid, Spain

Location status: Recruiting

Location contact

Alejandro Herrera Rojas, Physical Therapist

CONTACT

[email protected]

+34 640944777

About this study

The primary objective of this research is to evaluate the psychometric properties and validity of a hand laterality discrimination task in a post-stroke population. The study design includes two identical measurement points to assess the reliability and accuracy of motor processing.

The experimental protocol is divided into two main components:

Single Reaction Time (SRT) Task: This task is used to establish a motor processing baseline by measuring the simple reaction time to a stimulus.

Hand Laterality Judgement Task (HLJT): A mental rotation task where patients are shown photographs of right and left hands at different angles of rotation. Participants must decide whether the hand shown is a right or a left hand. The variables analyzed are the accuracy rate (percentage of correct responses) and the decision-making time (latency).

Upon completion of the HLJT, a structured interview is conducted to identify the mental strategies used during the task. This allows researchers to determine whether patients relied on motor imagery (e.g., mentally moving their own hand) or external visual strategies to achieve the results.

To complement these data, the study incorporates validated motor and kinesthetic imagery scales to assess the subjective quality of movement representation. Furthermore, demographic data (such as age and time since stroke) and cognitive variables are collected to control for potential confounding factors that may influence performance on the laterality tasks.

To evaluate the changes and the validity of the measurements, an Analysis of Covariance (ANCOVA) will be performed. In this model, the baseline measurement (Session 1) will be included as a covariate to control for initial individual differences in reaction time and accuracy. This approach allows for a more precise estimation of the task's stability and the effect of the variables studied by reducing the error variance associated with the participants' starting scores.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults (>18 years old) with Stroke
  • MoCA score > 21 points

Exclusion criteria

  • Other neurological conditions
  • Severe cognitive impairment

Treatment and study plan

Primary outcomes

  1. Hand Laterality Judgement

    Time frame: At baseline + a follow-up 1 week later

    Ability to disclosure right/left hand laterality

  2. Single Reaction Time Task

    Time frame: At baseline + a follow-up 1 week later

Study contacts

Contact information is provided by the study sponsor or research team.

Alfredo Lerín Calvo, Physical Therapist

CONTACT

[email protected]

+34 620187457

Marcos Moreno Verdú, Physical Therapist

CONTACT

[email protected]

+34 630 01 29 25

Sponsors and collaborators

Lead sponsor

Alfredo Lerín Calvo

Other

Collaborators

  • KU Leuven

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Mar 27, 2026
Registry last updated
Mar 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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