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Completed

NCT Number: NCT05663541

Validity and Reliability of Lower Extremity Position Test in Patients with Multiple Sclerosis

Sensory disorders are one of the most important problems in individuals with MS, and these disorders are among the first symptoms of MS. Loss of sense of proprioception is particularly common in patients with MS. Studies show that assessment methods for the quantitative measurement of sensory disorders are lacking. Especially in the clinic, there is no evaluation method that evaluates the sense of proprioception. Therefore, the aim of this study perform the validity and reliability study of the lower extremity position test to evaluate proprioception sense in individuals with MS.

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Key information

Conditions

Multiple Sclerosis Autoimmune Diseases Autoimmune Diseases of the Nervous System Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Immune System Diseases Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Proprioceptive Disorders Reliability Sensation Disorders Sensory Impairments Signs and Symptoms Somatosensory Disorders Validity

Age range

20 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Romatem Bursa Fizik Tedavi ve Rehabilitasyon Hastanesi

Bursa, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 20-65 years old
  • EDSS score between 0-5
  • Person who has not had an attack in the last 1 month or who is not in the attack period
  • Person without systemic disease such as hypertension, heart disease, Diabetes Mellitus, hyperlipidemia, malignancy
  • Person who has not undergone surgery that restricts balance function in the lower extremity.
  • Person without hip, knee and ankle contracture
  • Person who does not have additional neurological disease
  • Person who does not use vestibulosupressants or drugs that may cause neuropathy and does not have a history of alcohol use
  • To have full cooperation and adaptation to the work
  • Individuals who agree to receive treatment will be included in the study.

Exclusion criteria

  • Being younger than 20 years old and over 65 years old
  • Being in the attack period
  • Hip, knee or ankle contracture
  • Being greater than EDSS 5
  • Having systemic diseases such as hypertension, heart disease, Diabetes Mellitus, hyperlipidemia, malignancy
  • Having an additional neurological disease
  • Having a vestibulospressant or drug or alcohol use habit that causes neuropathy
  • Not cooperating and adapting to the work

Treatment and study plan

Lower extremity position test

Diagnostic Test

Assessing proprioception of the lower extremity of individuals multiple sclerosis

Primary outcomes

  1. Sensorial Assessment-1

    Time frame: through study completion, an average of 1 year

    Lower Extremity Position test

  2. Sensorial Assessment-2

    Time frame: through study completion, an average of 1 year

    Kinesthesia (Inclinometer)

  3. Balance Assessment-1

    Time frame: through study completion, an average of 1 year

    Static Balance via single leg stance

  4. Balance Assessment-2

    Time frame: through study completion, an average of 1 year

    Dynamic Balance via time up and go

  5. Walking Speed Assessment

    Time frame: through study completion, an average of 1 year

    The 10 meter walk test

Secondary outcomes

  1. Demographic Assessment

    Time frame: through study completion, an average of 1 year

    Demographic form

  2. Expanded Disability Status Scale (EDSS)

    Time frame: through study completion, an average of 1 year

    Ranges from 0 to 10 in 0.5 unit increments that represent higher levels of disability.

Sponsors and collaborators

Lead sponsor

Pamukkale University

Other

Registry information

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Dec 23, 2022
Registry last updated
Dec 5, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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