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Completed

NCT Number: NCT02883504

Validation Study of the Accuracy of E/e' in Estimating Left Ventricular Filling Pressure

The non-invasive estimation of left ventricular end diastolic pressure (LVeDP) is a main goal for performing an echocardiography in the routine clinical practice. Conflicting evidence exists about mitral E/e' ratio reliability for predicting high LVeDP

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Key information

Conditions

Doppler Echocardiography

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU Rennes

Rennes, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age over 18 years
  • Patient performing an echocardiography in the routine clinical practice
  • Informed consent given

Exclusion criteria

  • Severe valve disease, valvular prostheses, calcification of the mitral valve, the history of myocardial infarction, atrial fibrillation, severe arrhythmias not allowing the Doppler analysis, pacemaker and any image by inadequate Doppler ultrasound
  • Major person under legal protection (backup justice, trusteeship, guardianship), person deprived of liberty.

Treatment and study plan

Echo-Doppler examination and left heart catheterization

Procedure

Primary outcomes

  1. Invasive evaluation of left ventricular end diastolic pressure

    Time frame: D0

    Left heart catheterization

Secondary outcomes

  1. Non-invasive evaluation of left ventricular end diastolic pressure

    Time frame: D0

    Echo-Doppler

Sponsors and collaborators

Lead sponsor

Rennes University Hospital

Other

Registry information

Acronym: EUROFILLING

Important dates

Study start
2014
Primary completion
2016
Study completion
2016
First posted
Aug 30, 2016
Registry last updated
Jun 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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