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NCT Number: NCT07423416

Validation of the Modified Cognitive Assessment Scale (MoCA Blind) for the Diagnosis of Postoperative Neurocognitive Disorders in Patients With Corneal Pathology in Russia.

Long-term observation has shown that patients with visual impairment often develop cognitive impairments. Due to the fact that patients who are planning to undergo corneal transplantation may have initial cognitive deficits, assessing cognitive function is an important aspect of work for both the anesthesiologist and the operating surgeon. Given the high significance of assessing cognitive function after anesthesia in ophthalmic surgery patients, it is relevant to adapt and validate the Russian version of the MoCA Blind test for subsequent use in clinical practice.

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Key information

Conditions

Postoperative Neurocognitive Disorders

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients with corneal pathology, including burns, ulcers, dystrophies, and keratoectasia, as well as those with a history of corneal injuries
physical status of I-III on the ASA scale.

Exclusion criteria

children
patients with sensorineural hearing loss
patients with chronic cerebrovascular disorders
patients with initially high levels of anxiety and depressive symptoms
patients with severe cognitive impairments.

Treatment and study plan

Neurocognitive testing

Diagnostic Test

The psychometric properties of the Russian version of the MoCA Blind scale were evaluated according to the following parameters: reliability (reproducibility and internal consistency), validity (content and construct), and sensitivity.

Primary outcomes

postoperative neurocognitive disorders

Time frame: From the moment of inclusion in the study until the end of treatment 90 days later

Postoperative neurocognitive disorders were identified by comparing the results of neuropsychological tests performed before surgery and on the 90th day after surgery. An individual Z-score was used for each domain of the test.

Study contacts

Contact information is provided by the study sponsor or research team.

Alexandr Alexandr Romanov

CONTACT

[email protected]

+79182942721

Sponsors and collaborators

Lead sponsor

The S.N. Fyodorov Eye Microsurgery State Institution

Other Gov

Registry information

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2027
First posted: Feb 20, 2026
Registry last updated: Feb 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.