Cambridge University Hospitals Foundation Trust
Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
NCT Number: NCT02598336
Measurements of Structured Light Plethysmography (SLP) using a chest wall movement based method will be compared to those obtained by spirometry using a flow based pneumotachograph method. This study will enable validation of SLP in children and adults by allowing direct comparison of simultaneous measurements of breathing sequences using the two measurement techniques.
The investigators will also examine, in a group of normal adults, repeatability of the agreement between the two devices, and whether the agreement is affected by a change in tidal breathing parameters.
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Notify Me6 year–80 year
All sexes
Interventional
Not applicable
Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
Measurements using the Structured Light Plethysmography method will be compared to those obtained by spirometry using a flow based pneumotachograph.
Spirometry is the gold standard for measuring lung function in both clinical support and research roles. Modern spirometers are high precision, reliable instruments enabling a large numbers of parameters relating to lung volumes and the rate of emptying the lungs during a forced expiration to be measured. The most common and accurate method to measure the patient's forced expiration is via pneumotachograph which measures the flow of air through a mouthpiece and integrates the signal to derive the volume expired.
Structured Light Plethysmography (SLP) system that measures changes of the chest and abdominal wall movement during breathing by modelling the thorax and abdominal surface defined by a projected structured light pattern which enables a grid of virtual parts to be formed, the movement of which is recorded by digital cameras. SLP provides non-contact assessment to provide lung function data utilising structured light technologies and enhanced imaging processing.
In this study direct comparison will be made of measurements recorded simultaneously using the two measuring devices in children and adults.
To examine repeatability of the agreement between tidal breathing parameters measured by two techniques, repeated measurements will be performed in each of a group of normal adult subjects. The investigators will also examine whether the agreement is affected by a change in tidal breathing parameters. To obtain a change in tidal breathing parameters, measurements will be recorded during resting spontaneous breathing and after a period of exercise to elevate Respiratory Rate.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Non contact device that uses light to record displacement of the anterior thorax and abdomen region
Other names: SLP
Device that measures airflow at the mouth using a mouthpiece
Time frame: 5 minutes
The volume of air a person can exhale during a maximal forced breath
Time frame: 5 minutes
The volume of air a person can exhale in one second during a maximal forced breath
Time frame: 5 minutes
The maximal flow a person can achieve during a maximal forced breath
Time frame: 5 minutes
Visual comparison of respiratory waveform shape and amplitude produced by pneumotachograph and SLP.
Time frame: 5 minutes
Tmings derived from the Respiratory Waveforms
Time frame: 5 minutes
Timings derived from the Respiratory Waveforms
Time frame: 5 minutes
Timings derived from the Respiratory Waveforms
Time frame: 5 minutes
Timings derived from the Respiratory Waveforms
Time frame: 5 minutes
Timing ratios derived from the Respiratory Waveforms
Time frame: 5 minutes
Timing ratios derived from the Respiratory Waveforms
Time frame: 5 minutes
Flow ratios derived from the Respiratory Waveforms
Pneumacare Ltd
Industry
Validation of Structured Light Plethysmography Against Spirometry in Children and Adults
Acronym: SLPvsPNT
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