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OpenTrials
Completed

NCT Number: NCT02310217

Validation of New Tools for the Assessment of Cognitive Functions and Connectivity Network in Hypertensive Patients

The relationship among hypertension, aging and cognitive decline is complex and not completely understood. Purpose of this project will be evaluating early markers of cognitive deterioration in patients with arterial hypertension. In particular, this cross-sectional observational study will be articulated in three phases:

1. Neuropsychological evaluation of general cognitive abilities 2. Identification and measurement of specific biomarker levels 3. Correlation among hypertension, cognitive abilities and biomarkers.

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Key information

Conditions

Hypertension Cardiovascular Diseases Cognition Disorders Cognitive Dysfunction Cognitive Impairment Mental Disorders Neurocognitive Disorders Vascular Diseases

Age range

40 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

IRCCS Neuromed

Pozzilli, (IS), 86077, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Males or females diagnosed with arterial hypertension between 40 and 65 years of age;
  • Written informed consent prior to enrollment in the study.

Exclusion criteria

  • Precedent acute myocardial infarction (AMI);
  • Previous stroke and/or transient ischemic attack (TIA);
  • Previous or concomitant neurologic or psychiatric pathologies;
  • Neurologic or psychiatric pharmacological therapy.

Treatment and study plan

Primary outcomes

  1. Cognitive abilities measured by validated neuropsychological test battery (Montreal Cognitive Assessment test, Verbal Fluency test,learning of couple words, Stroop test)

    Time frame: 18 months

Sponsors and collaborators

Lead sponsor

Neuromed IRCCS

Other

Registry information

Important dates

Study start
2015
Primary completion
2020
Study completion
2020
First posted
Dec 8, 2014
Registry last updated
Apr 20, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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