Validation of Drug Assays in Various Biological Matrices

This study aims to ensure that assays that measure drug concentrations are accurate and precise in different matrices when quantified using high performance liquid chromatography -tandem mass spectrometry (HPLC-MS/MS). The study involves collecting samples of various bodily fluids to quantify antimicrobials, antivirals, oral contraceptives and erectile dysfunction agents. Samples will also be obtained from individuals not receiving these medications for quality control purposes.

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Key information

Conditions

Infection Infections

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Royal Liverpool University Hospital

Liverpool, L7 8XP, United Kingdom

Location status: Recruiting

Location contact

Helen Reynolds

CONTACT

[email protected]

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

> 18 years of age

Exclusion criteria

Unable to give informed consent

Treatment and study plan

antivirals, antimicrobials, oral contraceptive, erectile dysfunction agents

Other

Primary outcomes

To measure drug concentrations using high performance liquid chromatography -tandem mass spectrometry (HPLC-MS/MS) (accuracy and precision of assays that measure drug concentrations)

Time frame: Follow up up to 5 years

Assay validation

Study contacts

Contact information is provided by the study sponsor or research team.

Helen Reynolds

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

University of Liverpool

Other

Registry information

Important dates

Study start: 2014
Primary completion: 2027
Study completion: 2027
First posted: Nov 5, 2014
Registry last updated: May 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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