Skip to main content
OpenTrials
Completed

NCT Number: NCT04666064

Validation of COVILUS Score in Patients Suspected of COVID-19 Infection in the Emergency Room

Covid-19 (English acronym meaning coronavirus disease 2019) is an emerging infectious disease caused by a strain of coronavirus called SARS-CoV-2. The current pandemic has resulted in a significant number of admissions in the emergency room (ER) due to suspicion of COVID-19 infection. Use of lung ultrasound is standard practice to diagnose acute respiratory failure in ER. Recently, typical lung ultrasonographic characteristics of COVID-19 disease has been described. The investigators demonstrated that the association of 4 signs in pulmonary ultrasound associated with a clinical sign (COVILUS score) could predict the occurrence of a positive RT-PCR in patients suspected of COVID-19 infection admitted to the emergency room. The investigators are going to conduct a new study to validate this COVILUS score in this type of patient. The main objective will be to validate the diagnostic performance of lung ultrasound in patients admitted to the emergency room with suspected COVID19 infection.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Covid19 COVID-19 Coronaviridae Infections Coronavirus Infections Infections Lung Diseases Lung Ultrasound Nidovirales Infections Pneumonia Pneumonia, Viral RNA Virus Infections Respiratory Complication Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

BAR

Amiens, 80054, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients admitted to ER for suspicion of COVID-19 infection who has a SARS-CoV-2 RT-PCR test and for whom the emergency doctor decide to perform a lung ultrasound as part of the BLUE protocol
  • Age> 18 years old

Exclusion criteria

  • patients < 18 years of age
  • patients under guardianship or curators
  • pregnancy
  • poor echogenicity due to the presence of an acoustic barrier (pneumothorax, subcutaneous emphysema, etc.)
  • patients with a suspected or proven acute lung disease (pneumonitis, acute respiratory distress syndrome (ARDS))
  • patients with chronic interstitial lung disease
  • patients who will refuse to give their consent.

Treatment and study plan

Covid19 RT-PCR

Diagnostic Test

patients admitted to ER for suspicion of COVID-19 infection will have a SARS-CoV-2 RT-PCR test

Lung ultrasound

Other

patients admitted to ER for suspicion of COVID-19 infection who has a SARS-CoV-2 RT-PCR test and for whom the emergency doctor decide to perform a lung ultrasound

Primary outcomes

  1. concordance between Covid19 RT-PCR results and lung ultrasound results

    Time frame: one week

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Registry information

Acronym: COVILUS2

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Dec 14, 2020
Registry last updated
Jul 21, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.